GI Oncology Now (@gioncnow) 's Twitter Profile
GI Oncology Now

@gioncnow

GI Oncology Now brings you the latest research and updates in #livercancer, #coloncancer, #pancreaticcancer, and more in the gastrointestinal oncology sphere.

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calendar_today21-08-2023 19:02:00

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โญWe interviewed Dr Amit Mahipal on a recent study of atezolizumab + bevacizumab as a first-line treatment for HCC. ๐Ÿ‘‰ Dr. Mahipal describes the benefits of the combination, and reviews the differences between Child-Pugh and ALBI scores for patients: buff.ly/3WQRZ2U

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๐Ÿ’‰ Standard treatment for esophageal squamous cell carcinoma includes neoadjuvant chemoradiation and esophagectomy, but the surgery is often linked to complications. ๐Ÿ”Ž The preSINO trial analyzed the efficacy of active surveillance after chemoradiation: buff.ly/4dXBglv

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โ“ What's the difference between Child-Pugh and ALBI scores? ๐Ÿ‘‰ Dr Amit Mahipal discusses the differing factors utilized by each test, as well as which one may better predict mortality or benefit: buff.ly/3WQRZ2U

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โ—๏ธTempest Therapeutics announced that a U.S. FDA end-of-phase 2 meeting garnered positive feedback for #amezalpat + atezolizumab and bevacizumab for 1L unresectable or metastatic HCC. ๐Ÿ”Ž The study will compare the combination with atezolizumab and bevacizumab: buff.ly/3YPCZVE

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๐Ÿšจ #ICYMI: The U.S. FDA has accepted a Biologics License Application for nivolumab (Opdivo) plus ipilimumab (Yervoy) as a first-line treatment for unresectable HCC. ๐Ÿ‘‰ The decision was based on results from the phase 3 CheckMate-9DW study: buff.ly/4dMlKIQ

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โญ #ICYMI, Dan Kaufman, professor of medicine at UC San Diego, discusses TGF-ฮฒ and how it is linked to the development of hepatocellular carcinoma. ๐Ÿ‘‰ Learn more about how TGF-ฮฒ inhibition works with anti-HCC CARs to promote anti-tumor activity: buff.ly/4cSOr6a

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โ“ What's the difference between Child-Pugh and ALBI scores? ๐Ÿ‘‰ Dr Amit Mahipal discusses the differing factors utilized by each test, as well as which one may better predict mortality or benefit in his discussion on atezolizumab with bevacizumab for HCC: buff.ly/3WQRZ2U

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๐Ÿ”Ž As monomodal data has shown a lack of proficiency in understanding diverse presentations of HER2+ gastric cancer, a recent study used a multimodal analytic approach to predict treatment responses to anti-HER2 or anti-HER2 combined immunotherapy: buff.ly/3TyJMzJ

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๐Ÿ“‹ While research has shown an increase in GISTs after GIST-specific histology coding, there is a lack of knowledge on updated data & trends. ๐Ÿ”ฌ A study from Christian รlvarez and colleagues sought to determine the epidemiology of GISTs across major organ sites: buff.ly/4g7tM11

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๐Ÿ’Š Treatment for ESCC consists of neoadjuvant chemoradiation and esophagectomy, but the surgery is linked to complications. ๐Ÿ”ฌ The preSINO trial analyzed the efficacy of active surveillance through clinical response evaluations after chemoradiation: buff.ly/4dXBglv

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๐Ÿ’Š Can adding oxaliplatin to doublet chemotherapy with fluoropyrimidine benefit older patients with unresectable metastatic colorectal cancer? ๐Ÿ”ฌ New research has examined the potential triplet therapy: buff.ly/47dEkHS

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๐Ÿฅ What happens when #endoscopists, #EUS imaging, and multimodal AI all work together to #diagnose solid #pancreatic #tumors? ๐Ÿ’ก Read more about the latest research here: buff.ly/4cVCSLt

๐Ÿฅ  What happens when #endoscopists, #EUS imaging, and multimodal AI all work together to #diagnose solid #pancreatic #tumors?

๐Ÿ’ก Read more about the latest research here: buff.ly/4cVCSLt
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๐Ÿ“ฃ #ESMO24 content coming your way ๐Ÿ’‰ #Firstline #triplettherapy in treatment-naive patients with #KRAS #G12C #mutated #mCRC demonstrated an acceptable #safety profile ๐Ÿง  Learn more: buff.ly/3zgpILk

๐Ÿ“ฃ  #ESMO24 content coming your way 

๐Ÿ’‰ #Firstline #triplettherapy in treatment-naive patients with #KRAS #G12C #mutated #mCRC demonstrated an acceptable #safety profile

๐Ÿง  Learn more: buff.ly/3zgpILk
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โœจ "Unprecedented" 5-year #survival benefit with #STRIDE regimen in #unresectable #HCC โœจ ๐Ÿ”Ž Check out the #ESMO2024 data here: buff.ly/3TqrWi0

โœจ "Unprecedented" 5-year #survival benefit with #STRIDE regimen in #unresectable #HCC โœจ 

๐Ÿ”Ž Check out the #ESMO2024 data here: buff.ly/3TqrWi0
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โ„๏ธ POLAR trial findings presented at #ESMO2024 lay the groundwork for combining #immunotherapy and #PARPinhibitors in #metastatic #pancreatic #cancer โ„๏ธ Read more: buff.ly/4emQ0ua

โ„๏ธ POLAR trial findings presented at #ESMO2024 lay the groundwork for combining #immunotherapy and #PARPinhibitors in #metastatic #pancreatic #cancer

โ„๏ธ Read more: buff.ly/4emQ0ua
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๐Ÿงซ The first #randomized study to use #liquidbiopsy #cetuximab rechallenge may offer a much-needed #alternative in #metastatic #colorectalcancer More here #ESMO24 ๐Ÿ‘‰ buff.ly/3zcJ301

๐Ÿงซ The first #randomized study to use #liquidbiopsy #cetuximab rechallenge may offer a much-needed #alternative in #metastatic #colorectalcancer

 More here #ESMO24 ๐Ÿ‘‰ buff.ly/3zcJ301
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๐Ÿงฌ #Novel #KRAS #mutation #degrader shows โœ”๏ธ positive #safety profile and #antitumor activity in #pretreated #pancreatic #cancer #ESMO24 ESMO - Eur. Oncology ๐Ÿงฌ Read more: buff.ly/3XGY2c3

๐Ÿงฌ #Novel #KRAS #mutation #degrader shows โœ”๏ธ  positive #safety profile and #antitumor activity in #pretreated #pancreatic #cancer #ESMO24 <a href="/myESMO/">ESMO - Eur. Oncology</a>

๐Ÿงฌ Read more: buff.ly/3XGY2c3