With ButovskyLab, we show that silencing TIM-3 in brain-resident immune cells prevents neurodegeneration in a mouse model of #Alzheimers disease. Deletion of TIM-3 in microglia enhances phagocytic clearance of toxic amyloid beta. nature.com/articles/s4158…

Thrilled to have collaborated with the amazing Kuchroo Lab! We uncovered that silencing of a GWAS-AD TIM-3 in an #Alzheimers model by supercharging microglial clearance of toxic amyloid beta. A big step forward for neuroimmunology and translational research!

We are excited to share our newest publication from the Blurton-Jones Lab, "Harnessing human iPSC-moceoglia for CNS-wide delivery of disease modifying proteins." sciencedirect.com/science/articl…

Congratulations to Jean Paul Chadarevian and the whole Blurton-Jones team for this beautiful piece of work: Harnessing human iPSC-microglia for CNS-wide delivery of disease modifying proteins." 👍👍👍

After 75 Years, an Alternative to Edman Degradation: A Mechanistic and Efficiency Study of a Base-Induced Method for N-Terminal Peptide Sequencing | Journal of the American Chemical Society UT Austin @UTAustinChem UT Austin Chemistry pubs.acs.org/doi/10.1021/ja…

Some media coverage of our recent study on how Tim-3 regulates microglial activity. ButovskyLab Gene Lay Institute of Immunology & Inflammation. Researchers Mass General Brigham Harvard Medical School gaining ground on Alzheimer’s disease whdh.com/news/researche… via @7NEWS

Today's live episode of Zoom In on Dementia & Alzheimer's is starting soon—just click to join, no registration needed! Guest expert Dr. Ronald Petersen, a distinguished Mayo Clinic investigator, will explore what we know about Alzheimer’s and how we can better understand what it

We are back next Thursday (May 1st) with two wonderful presentations 📅Register now: zoom.us/webinar/regist… And remember, you can stay up to date on webinars, events, and more by subscribing to our mailing list: forms.gle/CJEGWiQ8SvkZ2d…

"Delivery Courier? Microglia Drop Neprilysin Off Near Plaques in Brain" alzforum.org/news/research-… Thank you Alzforum for highlighting our recent work from the Blurton-Jones Lab

Thanks to CAN ACN and CIHR for choosing my work on human CD33 isoforms in Alzheimer’s disease for a #brainstar_award. I share the credit with Matt Macauley UAlbertaScience UAlberta Research and all the amazing co-authors.

Dr. Ghazaleh Eskandar-Sedighi, from Blurton-Jones lab awarded prestigious Postdoc Fellowship from BrightFocus Foundation. She leverages human stem cell-derived microglia & chimeric animal models to examine protective microglial responses in AD. To read: mind.uci.edu/blog/

On-demand microglia deliver the therapeutic payload in Alzheimer’s disease. Cell Stem Cell cell.com/cell-stem-cell…

Thanks to ⁦UCI Charlie Dunlop School of Biological Sciences⁩ for the shoutout. Beyond grateful to have the support of ⁦BrightFocus Foundation⁩ in this exciting journey. And special thanks to ⁦Blurton-Jones Lab⁩ for their amazing leadership and continuous support of my research. bio.uci.edu/uc-irvine-post…

📢 Meet our newest grant recipients across Alzheimer’s disease, macular degeneration, and glaucoma research! These exceptional investigators, selected for their potential to bring us closer to cures by pursuing the untried, the unexpected, and the most promising ideas,

Identification of CD33m as a new protective factor in Alzheimer’s Disease development. Read about this research by Brain Star Award winner Ghazaleh Eskandari-Sedighi can-acn.org/brain-star-awa… University of Alberta Ghazaleh Eskandari-Sedighi @cihr_irsc

Excited to join the Early career editorial board of Molecular Biology of The cell (MBoC). As the official journal of American Society for Cell Biology, MBoC is dedicated to publishing high quality work. If you’re working on something that can be a good fit please DM me.

🚀 ISMND NextGen 2025 – Program at a Glance! Join us August 25–26 for an exciting opportunity to connect with peers, hear cutting-edge research, and be part of the next generation of neurodegeneration research! 👉 Register today and join us! bit.ly/43gHt8c

🙌A huge thanks to the organizers for putting together a brilliant program for #RTN2025 🧠 - IdoAmitLab Jonathan Kipnis 💔🎗️ beth stevens Rejane Rua Fran Quintana Lab. Also grateful to our many sponsors, speakers, attendees & vital team behind the scenes for an awesome meeting of the minds

#RTN2025 was such a blast. Amazing meeting, with tons of inspiring science and conversation. And an amazing cohort of next gen scientists to share some fun moments with ⁦Siling Du⁩ ⁦Jean Paul Chadarevian⁩