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Finally out… after 5 years of work, proud to be the editor responsible for the complete update of the Neurodegenerative disease section for the legendary Greenfield’neuropathology.

Dr. Gabor Kovacs’ team at Krembil Brain Institute has characterized the diversity in the neuropathological changes responsible for #Alzheimers, including a novel subtype, paving the way for personalized care. Read more ➡️ uhnresearch.ca/news/unlocking… The National Institute on Aging (NIA)

Our new review on molecular pathology of Neurodegenerative diseases search.app/Dipa6VZ7nLizhS…

Major messages of our recent paper: Neurodegenerative proteins affect different subregions of the hippocampus; copathology alters the pattern; The load of protein increase until a peak but in the highest stages it decreases with the loss of neurons. See: doi.org/10.1002/alz.14…

Glad to receive this Award… PS. Unfortunately Clarivate did not link my UofT and UHN affiliation correctly in the list despite my request.

HLA locus in progressive supranuclear palsy (PSP): 1) Some HLA alleles/haplotypes are overrepresented in PSP, one of which is associated with narcolepsy. 2) Binding prediction and modelling revealed strong-binding tau peptides. Autoimmune component ? biorxiv.org/content/10.110…

Agree- a lot of misleading documentation also of neuropathology data. I feel we don’t have the time and energy to comment on all articles that did not show transparently the results. Guidelines are needed how to present neuropathology results…as they started to do eg for blots

➡ rcpa.me/PathJournalMar… In the March special issue of #Pathology, Forrest and Gabor G. Kovacs MD PhD FRCPC provide an overview of the pathogenesis, diagnostic implications, and recent molecular and ultrastructural classifications of neurodegenerative diseases. They discuss how to approach

Why academia is sleepwalking into self-destruction. My editorial Brain If you agree with the sentiments please RT. It's important for all our sakes to stop the madness academic.oup.com/brain/issue/14…

“Rare disorders can occur in the same individual and be overlooked, especially when there is more obvious pathology.” onlinelibrary.wiley.com/doi/10.1111/ne…

Brief Interview with Toronto Dementia Research Alliance (TDRA) is online: youtube.com/watch?v=dqihr-… Thanks for Natalie Dren’s (TDRA)work on this.

New post in the TDRA Spotlight Blog Series! Dr. Gabor Kovacs (Gabor G. Kovacs MD PhD FRCPC) from University of Toronto and University Health Network discusses his research on cognitive decline and movement disorders. He focuses on early diagnosis, tracking disease progression, and personalized treatments. youtu.be/dqihr-JEwDA?si…

Pretty unexpected finding: Chronic traumatic encephalopathy in a Central European homeless cohort. “Violent behavior and various mental illnesses reported in homeless might not only be the cause, but also the consequence of CTE-NC.” link.springer.com/article/10.100…

Very happy that this paper is published. Novel aspects on the importance of HLA and potential autoimmune mechanisms in Progressive Supranuclear Palsy. sciencedirect.com/science/articl…

More to the story than #CTE. Head trauma may contribute to the development of astrocytic tau pathology reminiscent of aging. Mechanisms of pathogenesis and clinical correlates will be important to determine. Penn Neurosurgery Dr Willie Stewart Gabor G. Kovacs MD PhD FRCPC Eddie Lee Andrea Schneider

🌐 Meet the final speakers of the first session of #aceResearchSummit: ✅ Michael Heneka, MD (University of Luxembourg) ✅ Maggie Flanagan M.D., MD (UT Health San Antonio) ✅ Gabor G. Kovacs MD PhD FRCPC, MD, PhD, FRCPC (University of Toronto) ✅ Marta Marquié, MD, PhD (Ace) Get your seat 👉: aceglobalresearchsummit.com

Further evidence that Progressive supranuclear palsy has prominent inflammatory associations. Indeed, this is different than that seen in Parkinson’s or Alzheimer’s. Time to reconsider PSP pathogenesis? academic.oup.com/brain/advance-…