New Preprint from the lab: how do phage tails polymerize? We used this monstrosity of a tail (nearly 1µm long!) from the thermophilic phage P74-26 to get some answers. biorxiv.org/content/10.110… 1/

I'm delighted to share the first paper from my PhD published in ACS Synthetic Bio! SpyPhage: A Cell-Free TXTL Platform for Rapid Engineering of Targeted Phage Therapies. doi.org/10.1021/acssyn… #TXTL #phage #phagetherapy #synbio #cellfree

Check out our new in press paper! How do some mutants, that appear antibiotic susceptible in vitro, protect themselves in vivo? They utilise host polyamines to make a protective coat. insight.jci.org/articles/view/… A thread

BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”

Super excited to share a big part of my postdoc work in the AdamArkin_Lab where I developed a new functional genomic platform to study gene functions in gut bacteria! See thread for a brief summary. 1/n #functionalgenomics #microbiome #DNAbarcoding biorxiv.org/content/10.110…

We’re excited to report today in @nature the cryo-EM structure of the OMEGA family member IsrB in complex with ωRNA and target DNA. nature.com/articles/s4158…

I might have been a tab bit overambitious in the initial pangenome building experiment.

The promise of the gut microbiome as part of individualized treatment strategies. Review article Nature Reviews Gastroenterology & Hepatology nature.com/articles/s4157…

Excited to see this work by Mengxiong Wu @jlli6t at UQ ACWEB Simon McIlroy Gene Tyson Centre for Microbiome Research et al has been published in Nature Communications. 5-year efforts to discover a novel organism able to #anaerobic oxidation of #propane coupled to #nitrate reduction. UQ News nature.com/articles/s4146…

Welcome to the Viruses of Microbes-UK (VoM-UK) twitter feed. This will support the annual VoM-UK meeting offering updates or information on the inaugural meeting on the 26th-27th Jan 2023 at Northumbria Uni.

NEW PIECE: The Many Shapes of Bacteria ⚪️🧫⚪️ #bacteria #microbes #infographic #art #sciart #scientificart #colony #microbiology #microorganisms #biology #microscopy #germs #science #illustration #petri #infographics

Global landscape of antimicrobial resistance nature.com/articles/s4146…

What has happened or is happening to this coral? Answers in the comments and i'll tell you if you are correct or not in 24 hrs

The Impact of Cyanobacteria Blooms on the Aquatic Environment and Human Health freshwaterecology.wordpress.com/2022/12/04/the…

Viruses are the most abundant biological entity in the #ocean. In this #PLOSBiology Essay, Flora Vincent @vardilab discuss interactions between hosts and #viruses in the ocean and their relevance for global ocean ecosystem function in a changing climate. plos.io/3kJcjDY

Our paper on the isolation and characterization of a small virus is out, and the time has come to say: 🔴virophage is a lifestyle🔴™️. This is a hill I will die on. 🌄nature.com/articles/s4156… 1/

1st ever VoM-UK meeting done. Great talks and fantastic people. Grateful to Darren Smith for the meething! Looking forward to the next edition

I have just realised we forgot to take the group delegates photo on the final day of VoM-UK. There were 124 attendees from as far North as St Andrews to as South as Southampton and Exeter Unis. Thanks for joining us at Northumbria Uni for the first of these annual meetings.

Evolution of virus and virophage facilitates persistence in a tripartite microbial system dlvr.it/ShpkNl

biorxiv.org/content/10.110… The evidence mounts: toxin/antitoxin systems now shown to inhibit RNA phage (E. coli MazF/MazE vs. RNA phage MS2 & Qbeta) and mechanism does not likely involve cell suicide.