Preston Ge (@ge_preston) 's Twitter Profile
Preston Ge

@ge_preston

he/him/his || MD/PhD candidate @HarvardMITmdphd || Heiman lab @mitbrainandcog || previously @JohnsHopkins

ID: 1046982161390362624

linkhttp://prestonge.science calendar_today02-10-2018 04:36:14

427 Tweet

359 Followers

316 Following

David Pla-Martín (@dpla_) 's Twitter Profile Photo

Have you ever wondered why mtDNA is maternally inherited? These guys found the answer! Because of TFAM!!! . Check out! nature.com/articles/s4158…

Xinhe Zheng (@xinhezheng) 's Twitter Profile Photo

How are diverse brain cell types impacted by diverse panels of disease-associated risk genes? Please check out our new work, massively parallel in vivo Perturb-seq, now on bioRxiv. We screen across AAV phylogeny to find a new serotype with rapid (2 day) expression onset 🚀 1/7

Leyla Akay (@leyla_aakay) 's Twitter Profile Photo

Are you applying to MIT's Dept. of Brain and Cognitive Sciences PhD program? The BCS Application Assistance program is a student-run group with the goal of providing assistance to prospective students navigating the application process. Sign up to talk to a mentor below:

Laurie Rumker (@laurierumker) 's Twitter Profile Photo

We are excited to share Genotype-Neighborhood Associations, GeNA, a new tool adapting our CNA framework to detect cell states associated in abundance with genetic variants at genome-wide scale in high-dimensional single-cell data w/ Soumya Raychaudhuri সৌম্য রায়চৌধুরী doi.org/10.1101/2023.1… 🧵

Hongkui Zeng (@hongkuizeng) 's Twitter Profile Photo

This is a landmark achievement that will open the door for many future investigations of the brain’s function, development and evolution. Congrats to everyone who has contributed to this monumental effort. Big thanks to the NIH #studyBRAIN Initiative for supporting this project.

Michelle Kuo (郭怡慧) (@kuokuomich) 's Twitter Profile Photo

I've read nothing like this before—a painfully honest piece about the cruelty and patriarchy of academia, viewed through the lens of a grieving wife. Lang Chen remembers the last days of husband Xiaohong Xu, a brilliant, beloved sociologist from China who passed away at age 45.

Martin Picard (@mitopsychobio) 's Twitter Profile Photo

How much energy do cells and organisms with impaired mitochondrial OxPhos waste in mounting (futile) stress responses? Could hypermetabolism - rather than ATP deficiency - cause symptoms and disability in mitochondrial diseases? nature.com/articles/s4225…

How much energy do cells and organisms with impaired mitochondrial OxPhos waste in mounting (futile) stress responses? 

Could hypermetabolism - rather than ATP deficiency - cause symptoms and disability in mitochondrial diseases?

nature.com/articles/s4225…
Preston Ge (@ge_preston) 's Twitter Profile Photo

In a world where scientific data are misrepresented to support racist viewpoints, it’s critical that we recognize how the way we visualize our data can be easily misinterpreted or co-opted by bad actors.

Vamsi Mootha (@vamsimootha) 's Twitter Profile Photo

Delighted to introduce PMF-seq: a new way to link genetic perturbations to detailed bioenergetic phenotypes. We use the method to dissect genetics of mitochondrial ETC branching and acute tBID action. Led by T.L.To ⁦Broad Institute⁩. nature.com/articles/s4225…

MIT Picower Institute (@mit_picower) 's Twitter Profile Photo

Excited to see this new paper in Science Magazine co-led by Linlin Fan: It shows, in live animals, a key mechanism of how circuits form to enable spatial memory. science.org/doi/10.1126/sc…

Steven Salzberg 💙💛 (@stevensalzberg1) 's Twitter Profile Photo

How many genes are in the human genome? (The third in an irregular series of threads about #Bioinformatics.) Let’s start by restricting “gene” to mean “protein-coding gene.” For the moment, this number appears to be just under 20,000, far lower than it used to be 1/11

Patrick Hsu (@pdhsu) 's Twitter Profile Photo

this is really cool and one of the most important frontiers in functional genomics: integrating genetic perturbation and complex functional phenotypes (beyond growth, resistance, engineered reporters, etc) can't wait until this is all optical and pooled

this is really cool and one of the most important frontiers in functional genomics: integrating genetic perturbation and complex functional phenotypes (beyond growth, resistance, engineered reporters, etc)

can't wait until this is all optical and pooled
MIT Picower Institute (@mit_picower) 's Twitter Profile Photo

New in Cell: Two neurodegenerative diseases, ALS and FTLD, share many cellular and molecular similarities that could be targeted for potential treatment. picower.mit.edu/news/movement-… @mitscience MIT Brain and Cognitive Sciences MIT CSAIL

Stanislovas S. Jankauskas, PhD (@ssjankauskas) 's Twitter Profile Photo

Redistribution of mitochondrial protein genes from mtDNA to nucleus early in evolution put a hard challenge for nervous system much later. Neurons need somehow to supply mito in axon terminals with proteins. And transport of substances through a long axons could take days - a

Redistribution of mitochondrial protein genes from mtDNA to nucleus early in evolution put a hard challenge for nervous system much later. Neurons need somehow to supply mito in axon terminals with proteins. And transport of substances through a long axons could take days - a