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🚨we have a PhD position open! New exciting project with baldocklab and Zacherchenko lab, combining: 🔎#ECMatrix (read: #collagen) 🏗️#Structural biology 🐣#Development in 🦴 Please share widely to budding matrix/structural aficionados! FindAPhD: findaphd.com/phds/projectde…

BBSRC RM applications funded! Hilary Ashe The Ashe lab and Martin Lowe:

Modeling of total #RNAseq time series data across early #Drosophila #embryogenesis provides estimates of mRNA half-lives; single-molecule imaging reveals that unstable mRNAs & 3' #mRNA fragments are enriched in P-bodies The Ashe lab #PLOSBiology plos.io/3CVSEai

Great to see this work from Lauren Forbes Jennifer Love and Yuliya Shapovalova as part of our collaboration with @MagnusRattray published! RNA-seq, mathematical modelling and imaging ⬇️🧬🧮🔬

We are hiring! There are TWO exciting new postdoc positions in the lab building upon our previous work on #BMP signaling both in the #Drosophila embryo and germline stem cells. Please RT and share, full details in the thread 🪰🧬🔬🥼

Really enjoyed hearing about all the cool science going on around me in Division of Molecular and Cellular Function UoM and pleased to have won a poster prize!

Excited to share our latest research out today in Cell Reports looking at transcriptional bursting of X chromosome genes in the Drosophila embryo. 🧬🔬 shorturl.at/xDL59

We’re really excited to share our latest paper published in NSMB on the structure of #fibrillin microfibrils by #CryoEM WTCCMR The University of Manchester nature.com/articles/s4159…

Grateful to be doing my PhD with such a great team of scientists (and flies 🪰)!

🙌Friday was the last day of the Computational Modelling of Multicellular Systems course. Below is a picture of all the participants and some of our teachers. It was great to have you here! #EMBOMulticellModelling EMBO EMBL Barcelona EMBL Events

Lab lunch today saying hello to our new post-doc Amanda and saying gooodbye masters student Harry- well done on your hard work! 😊🪰🔬

Please RT - we are looking for a postdoc to investigate how signalling filopodia collect and transduce the #BMP signal in #Drosophila ovarian germline stem cells, collaborating with Shukry J Habib in beautiful Lausanne! 🪰🏔️ Full details in the ad: jobs.manchester.ac.uk/Job/JobDetail?…

It's that time of year again - we are collecting donations of festive food and gifts for Emmeline's Pantry New to help support local families this Christmas 🎁 The collection will run throughout November - please get in touch if you wish to get involved! 🎅 Division of Molecular and Cellular Function UoM UoM Biology, Medicine and Health

The evolution of multicellular organisms led to the development of body structures and functions. During embryogenesis, establishing three body axes–anterior-posterior (head-to-tail), dorsal-ventral (back-to-belly), and left-right–is essential for the organism's development. 1/n

Absolutely delighted to share this work on the conserved interaction between Twisted gastrulation and BMPs! Congratulations to my co-first authors Tomas Tomas Malinauskas and Amalie, and the entire team! Take a look here: nature.com/articles/s4146…

Authors from The Ashe lab, @BaldockLab including Tomas Malinauskas and Gareth Moore report structures of TWSG1 in complex with a BMP ligand and show how TWSG1 inhibits signaling. nature.com/articles/s4146…

Congratulations to Kerim Anlaş, Nicola Gritti & Trivedi Lab EMBL Biomedicina BCN for the work on early autonomous patterning of the anteroposterior axis in gastruloids Development. doi.org/10.1242/dev.20…

Glad to share the second half of my work on Tsg focusing on the second half of the protein! Read below for modelling, mutations, embryos and even a bit of evo-devo! 🪰

We are excited to share the latest contribution from the lab! We found that cells in gastruloids communicate to each other in order to control the timing of gastruloid symmetry breaking.