New preprint from the lab! Led by Tiffany Cho we employed CRISPR-based fitness screens to chart the response to ubiquitin E1, SUMO E1, NEDD8 E1 and p97/VCP inhibitors. 🧵1/5 biorxiv.org/cgi/content/sh…

Many congratulations to AH for being approved for the PhD degree. The first Balmus Lab PhD student and already on to a powerful start at Vertex Pharmaceuticals! Well done Arshad!

Two postdoc positions in my lab are advertised. Join us in the Balmus Lab balmuslab.org jobs.cam.ac.uk/job/43226/ jobs.cam.ac.uk/job/43231/

A novel target for neuroprotection in #PD: Our new study was just published in Nature Communications by Tracy Zhang from our lab & collaborators Cambridge University & Mission Therapeutics on knock-out and inhibition of USP30 in an alpha-synuclein mouse model nature.com/articles/s4146…

Incredible Lab Retreat culminating in a Festive Christmas Dinner hosted by the Balmus Lab!

I am very proud of our paper on micronucleus formation published today in nature with David Adams and our collaborators!!! Cambridge University UK Dementia Research Institute Wellcome Sanger Institute @TINS nature.com/articles/s4158…

100+ genes linked to DNA damage have been uncovered in new research 🧬 The findings provides insights into DNA damage tied to #ageing, #cancer and #Alzheimers and identify new drug targets🧠🎯 sanger.ac.uk/news_item/key-…

We have open postdoctoral positions to investigate the role of DNA repair proteins in anti-tumor immunity and study the DNA damage response at nucleotide resolution with base editing screens. Come and join us! Columbia Genetics and Development Department Herbert Irving Comprehensive Cancer Center Columbia Stem Cell Initiative (CSCI) ciccialab.com

Scientists identify genes linked to DNA damage and human disease shar.es/agrfIb

Interesting new study by Dr Emmanouil Metzakopian investigates the interplay between mitochondria-endoplasmic reticulum contact sites - essential in cells for functions including calcium homeostasis👏 The findings could lead to new therapeutic targets👉buff.ly/49ODH8e

New research reveals the power of microglia in smouldering MS | MS Society | kudos to ⁦MS Society UK⁩ for continuous support with ⁦L Peruzzotti-Jametti⁩ ⁦Cory Willis⁩ ⁦Grzegorz Krzak⁩ ⁦Cam Neuroscience⁩ ⁦Cambridge University⁩ mssociety.org.uk/research/lates…

Congratulations Pluchino lab - Regenerative Neuroimmunology and L Peruzzotti-Jametti! What a great story! We have been delighted to be part of the team! nature.com/articles/s4158…

A postdoc position is available to join the group as part of an international consortium to address bottlenecks in early detection of ovarian cancer. Have a look here to find out more and apply if you're interested: jobs.manchester.ac.uk/Job/JobDetail?…

We are hiring! The Ochs Lab is looking for an enthusiastic & collegial Postdoc to join us at @UCPH_BRIC in Copenhagen, Denmark. if you are interested in chromatin organisation and genome maintenance mechanisms, find the full ad below: candidate.hr-manager.net/ApplicationIni…