Is exome sequencing the most powerful tool ever invented to reduce the risk of death?

We identified for the first time a selection of three cancer driver mutations (P53, KRAS and VHL) during CRISPR-Cas9 gene editing and chart a comprehensive gene-wise editing risk map in our new work out today. This series summarizes it 1/X biorxiv.org/content/biorxi…

This was cool to write up -- As CRISPR horizons cloud, a startup focuses on the next big thing with powerhouse potential — the RNA editing platform endpts.com/as-crispr-hori…

As CRISPR horizons cloud, a startup focuses on the next big thing with powerhouse potential — the RNA editing platform - endpts.com/as-crispr-hori…

Keep an eye on these 7 startups in 2020 Kevin J. Ryan inc.com/kevin-j-ryan/i… via Inc.

In this thread I provide information on inflammation and therapeutic interventions for SARS-CoV2 / COVID-19. The spirit of the thread is to encourage discussion on an important topic in light of numerous clinical interventions (see Figure below). Please read on...

Welcome to our two newest board members! Gayathri Rajan and Kelly Sims have years of experience leading tech platform companies Google and Stripe, and will bring their expertise to the next phase of our business. More here: bit.ly/37NWMMV

Genome-wide mapping of mutations at single-nucleotide resolution for protein, metabolic and genome engineering go.nature.com/2hqh00Q

IgDiscover published in Nature Communications ift.tt/2hTzHu2

Pancreatic #cancer mets: driver mutations & epigenomic reprogramming nature.com/ng/journal/vao… nature.com/ng/journal/vao…

Single-cell sequencing reveals {alpha}{beta} chain pairing shapes the T cell repertoire biorxiv.org/cgi/content/sh… #bioRxiv

How many proteins molecules in a cell? 42 million in a simple cell (yeast), quantified for the first time ? N in human cell cell.com/pb-assets/jour… Cell Systems Cell Press by University of Toronto

Our Nature Biotechnology paper on DNA data storage is up. Enjoy! "Random access in large-scale DNA data storage" nature.com/articles/nbt.4…