De novo RNA tertiary structure prediction at near-atomic resolution using deep learning: DeepFoldRNA significantly outperforms state-of-the-art! If it indeed works, it would be a huge leap forward in RNA structure prediction! biorxiv.org/content/10.110…

Selective inhibition of protein secretion by abrogating receptor–coat interactions during ER export | PNAS pnas.org/doi/10.1073/pn…

Chaperone-Directed Ribosome Repair after Oxidative Damage | bioRxiv biorxiv.org/content/10.110…

Super cool story! embopress.org/doi/full/10.15…

Monitor autophagic flux in mammalian cells easily with our new method, now out in eLife - the journal! Pulse-labeled HaloTag reporters are processed in lysosomes, releasing proteolysis-resistant labeled Halo. Free labeled Halo amount = autophagic flux! →western/in-gel fluo/microsc./flow cyto

Nondegradable ubiquitinated ATG9A organizes Golgi integrity and dynamics upon stresses: Cell Reports cell.com/cell-reports/f…

Our structure of dynein-dynactin on microtubules is now out in nature! Thanks to Janet Iwasa for this beautiful movie showing how cargos might use pairs of adaptors to recruit their motors. nature.com/articles/s4158…

We have been selected as one of John Carroll' 11 most promising startups in the biotech industry. We're thrilled to have been able to bring together a fantastic team to advance our shared mission and are excited to see what the future holds endpts.com/the-endpoints-…

ER-Golgi-localized proteins TMED2 and TMED10 control the formation of plasma membrane lipid nanodomains cell.com/developmental-…

Please spread the news… we are going to recruit 3 PhD students on our ERC funded project lipotrace!!! So if interested in time resolved single cell lipidomics join us at EPFL ;)

Calcium transients on the ER surface trigger liquid-liquid phase separation of FIP200 to specify autophagosome initiation sites cell.com/cell/fulltext/…

NEW ONLINE: Differential ribosomal gene RPL22L1 splicing isoforms are generated in response to acidification of the glioblastoma core to regulate cell stemness and survival and increase tumour heterogeneity. PDF: rdcu.be/cWT8a nature.com/articles/s4155…

Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage | Journal of Cell Biology | Rockefeller University Press rupress.org/jcb/article/22…

Robust and Versatile Arrayed Libraries for Human Genome-Wide CRISPR Activation, Deletion and Silencing | bioRxiv___The name they gave to the libraries is the most amazing thing, love it! biorxiv.org/content/10.110…

Why Elephants Don't Get Cancer - Scientific American scientificamerican.com/article/why-el…

Juan Carlos Izpisua Belmonte was recognized as the recipient of the 2022 Ogawa-Yamanaka Stem Cell Prize this week at a ceremony in San Francisco. We’re proud to see him honored for his contributions to the field.

5,562 proteins were found to have tissue-specific enrichment across 32 human tissues. The majority of them (3,088) are enriched at the protein but not RNA level. The brain hosts the largest number of proteins that are only enriched at the protein level but not RNA level.

Hi 👋 science twitter! Are you into genetic screens and small molecule drug discovery? We are looking for a pharmacogenomics enthusiast! The position will be located at Altos Labs in Cambridge UK and is part of our Institute of Medicine Pls RT! boards.greenhouse.io/altoslabs/jobs…

Fantastic work from my lovely friend and amazing scientist Maddalena Nano leveraging precision biology to show that caspase activation does not irreversibly commit cells to death. Definetely worth reading!#anastasis #PNAS pnas.org/doi/10.1073/pn…

CCPG1 recognizes ER luminal proteins for selective ER-phagy | Molecular Biology of the Cell molbiolcell.org/doi/10.1091/mb…