Year 13 students worked on the first stage of creating a recombinant plasmid for production of the red fluorescent protein (rfp). They used restriction digestion with two enzymes (BamHI and HindIII) to create linear DNA fragments from 2 known plasmids Amgen Biotech Experience (ABE) Program Office Centre for STEM Education

Year 13 learnt about an essential tool which is used in genetic engineering; DNA ligase. They used this to catalyse covalent bond formation between the linear fragment with sticky ends. Aiming to make the recombinant plasmid pARA-R containing both the rfp gene and the ampR gene

Have Year 13 been successful in making their recombinant plasmid? Well today they are a step closer to finding out by using agarose gel electrophoresis and then staining the DNA bands. The gels will be visualised tomorrow using a UV transilluminator Centre for STEM Education Amgen Biotech Experience (ABE) Program Office

Year 13 Biologists have had success in making their recombinant plasmid. Their gels were visualised Friday using a UV transilluminator #biotech #biotechexperience Dr. Phil Smith Amgen Biotech Experience (ABE) Program Office Centre for STEM Education

All Year 13 Biologists successfully transformed bacteria, well done Dr. Phil Smith Amgen Biotech Experience (ABE) Program Office Centre for STEM Education #biotechexperience

Today Year 13 Biologists explored one of the many uses of the polymerase chain reaction (PCR), learning about the enzyme DNA polymerase, sequence specific primers and thermal cycling. Dr. Phil Smith Centre for STEM Education Amgen Biotech Experience (ABE) Program Office #BiotechExperience

Year 13 visualised the size of the PCR product, made yesterday, from a red bacterial colony using agarose gel electrophoresis, allowing the size of the DNA product (which is dependent on the genotype) to be correlated with the colour of the transformed bacteria (the phenotype).

GCSE Religious Studies students spent the day exploring the beautiful and edificial Ely Cathedral, including climbing all 66 metres to the top of a windy West Tower. They gained valuable insight and ideas which will benefit them in their exams.

Super sleuthing today for Year 9s as they try and work out who murdered the Principal of Saxtead College, Mrs South. 😱 Scientific, maths and language skills needed. WHO? WHY? HOW? #CSI Framlingham College

Excited to be hosting the UKMT Regional Team Maths Challenge today at the College. Stay tuned for updates and results this afternoon!

Congratulations to Titanic Investments, Arthur O., Ben S., Tom C. and Theo S., who have reached this year's final of the Student Investor Challenge! The initial trading competition attracted over 30,000 students and 10,000 teams. Read more: framlinghamcollege.co.uk/student-invest…