An update on probe of Missouri human case of H5 bird flu that CDC confirmed last week Spokesperson for state health department says: "All contacts remained asymptomatic throughout the observation period." tinalexander.github.io/notes/2024/09#…

🆕🇺🇸 Minnesota has released most of its reported herds from #H5N1 #BirdFlu quarantine. ▶️ Only 1 herd remains under quarantine ▶️ Avg. dairy herd quarantine duration: 64 days (min 47, max 92) bah.state.mn.us/h5n1

Interesting details on sequencing efforts for the #H5 bird flu case in Missouri from NIAID Director Jeanne Marrazzo via Alexander Tin : "The CDC... is continuing to try to sequence the relative relevant parts of what they got." "it’s almost certainly consistent with the bovine

We've been sequencing wastewater for 2.5 years. In 2024, H5N1 started showing up. Our findings are published in the New England Journal of Medicine. Sequencing-Based Detection of Avian Influenza A(H5N1) Virus in Wastewater in Ten Cities w/ Texas Epidemic Public Health Institute nejm.org/doi/full/10.10…

⚠️🇺🇸 USDA confirms 2 more California dairy herds tested positive for #H5N1 #BirdFlu, bringing CA total to 8 since Aug 30. ▶️ Total H5N1 detections in US livestock: 204 herds in 14 states since Mar 2024. aphis.usda.gov/livestock-poul…

🆕🇺🇸 USDA voluntary milk-tank testing program for #H5N1 #BirdFlu increased to 46 herds (+5): ▶️ Virginia joined with 1 herd ▶️ Michigan added 4 more herds While the increase is slow, it reflects rising farmer awareness, though participation remains low. aphis.usda.gov/livestock-poul…

⚠️🇩🇪 Germany reported new #H5N1 #BirdFlu in a poultry farm in Leuna. 🦆198 birds (98 geese, 100 ducks) affected, 54 dead, 144 culled. ℹ️Last outbreak occurred 32 days ago on Aug 11 in northeastern Germany (2 farms affected). wahis.woah.org/#/in-event/586…

The NEJM paper on sequencing wastewater for #H5N1 is particularly important because it allows us to understand when the virus is adapting toward human-human transmission. It seems that multiple mutations would be necessary for this scenario to occur, but knowing when it is

The plot thickens: CDC says a close contact of the Missouri #H5 #birdflu case was sick at the same time but wasn't tested. Not clear why that info wasn't shared Thurs during an hour-long press briefing when CDC said Missouri was looking like a "one-off" case.

🚨📣 Anticipated sequence from human #H5N1 case in Missouri w/ lack of clear exposure source, just released by CDC Flu through GISAID Initiative [EPI_ISL_19413343]. Clade 2.3.4.4b, similar to dairy cattle H5N1 virus. Sample collected 8/22/24, sequence took over 3 weeks to release! Source

🆕🧬 CDC submitted Missouri #H5N1 human case genome sequence to GISAID. HA/NA phylogenetic analysis shows close relation to bovine H5N1 viruses. PB2 pending. gisaid.org/resources/gisa… #BirdFlu

🆕 H5N1 Weekly Update: 7 - 13 Sep 2024 From Missouri's unexpected #H5N1 #BirdFlu human case to global outbreaks, get your concise weekly snapshot of key H5N1 developments worldwide. 👉Read more fluradar.substack.com/p/h5n1-weekly-…

#H5N1 updates Interestingly the recently uploaded sequence from the human #H5N1 case (MO) shares HA mutations with another sequence from Dairy Cow Milk [HA: P152S and A172T] Meta data indicates this sequence is from individual cow milk (collection date 04/08/2024).

Shared exposure? Food poisoning? Missouri's health department confirms "household contact" of bird flu case sickened last month Both had symptoms onset "on the same day" Contact wasn't tested because "too late for PCR testing to occur effectively" tinalexander.github.io/notes/2024/09#…

Analysis of the #H5N1 sequence from the presumed H2H transmission in Missouri finds two concerning mutations: 1. Likely reduces effectiveness of antibodies derived from the current H5N1 vaccine. 2. May moderately increase infective in humans.

⚠️🇺🇸 USDA confirms 4 more #H5N1 #BirdFlu cases in dairy herds in 3 states: Texas (2), California (1), Idaho (1). ▶️ State totals: Idaho (32), Texas (26), California (9) ▶️ Total H5N1 detections in US livestock herds: 208 across 14 states since Mar 2024. aphis.usda.gov/livestock-poul…

Turlock, California H5 detection, second in September, again a bolus which might come from heat-treated milk at a dairy or discarded milk from a Grocery store. Helen Branswell 🇨🇦 Tom Peacock 0bFuSc8 Marc Johnson CDC Flu FluRadar

New CDC study: 75% of US adults support wastewater monitoring, and 95% say they would take steps to protect themselves if wastewater data showed disease spread was high. We need to fund wastewater monitoring and include the data in daily weather reports, so everyone is aware.

📊 This week in #H5N1 #BirdFlu: ▶️ CA: 9 new dairy cases, now 17 total since Aug 30 ▶️ CA: 1st commercial poultry flock outbreak since Jan ▶️ MA: All 95 dairy farms test negative ▶️ New study on potential pre-existing immunity in humans Latest report: fluradar.substack.com/p/h5n1-weekly-…

⚠️🇺🇸 USDA confirmed 18 more #H5N1 #BirdFlu cases in California dairy herds, state total now 34 since Aug 30. ▶️ US livestock total outbreak: 233 in 14 states since March. ▶️ Record single-day increase, likely more herds to be reported in coming days. aphis.usda.gov/livestock-poul…