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Do you want to learn how the first cancer mutations are established? We show that they first manifest as lesions (alteration on one DNA strand) & are then carried over multiple cell generations before finally being established as mutations. Have a go at this great tweetorial 👇

"...the most striking difference is that UMAP produces denser, more compact clusters than t-SNE, with more white space in between." It still confuses me when some papers use t-SNE for some figures and then all of the sudden UMAPs for no apparent reason. biorxiv.org/content/10.110…

Somehow I had missed this gem showing the effects of technical sampling on estimating transcript distributions across single cells doi.org/10.1016/j.cels…

Data Scientists should pay more attention to the color blind minority. Using the viridis color scale for continuous and ggthemes' scale_colour_colorblind for discrete data should do the trick, I believe.

Bioinformatic pipelines

There are plenty of ways to waste time online. You already know those. Instead, here are 7 sites that will make you more productive––not less: 🖥

Computational Biologist wanted! If you're a bioinformatician with a PhD, consider joining this amazing team: jobs.gsk.com/en-gb/jobs/336… Ping me for questions.

Skip this unless you are starting as a software developer. Here are 11 short problems that will help you practice. As you move through the list, their complexity increases. It doesn't matter the language you are learning. Try them out! ↓