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Respect for Tor Biering-Sørensen, MD, MSc, MPH, PhD et al who’ve executed E-nudge intervention RCTs via the Danish national registry 🌟present’n by Ankeet S. Bhatt, MD, MBA on pooled analysis of 3🇩🇰 #NudgeFlu trials #AHA24 Nudges w CV message ⬆️ uptake of #Flu💉 in #postMI patients How can we adopt results broadly?

CTCPR Trials & CIRL is yet again revolutionizing the RCT landscape. First patient randomized in the DAN-RSV trial, which will test whether a RSV vaccine reduce the risk of being hospitalized for RSV. We aim to randomize ~ 130000 Danish citizens during the next 6 weeks clinicaltrials.gov/study/NCT06684…

New RSV vaccine RCT! 🚨 This week we started recruitment for the DAN-RSV trial 130.000 👴🧓 60+ years will be randomized 1:1 to RSVpreF vaccine 💉 or no RSV vaccine Prim endpoint: RSV-related resp disease hosp 🏥🦠 Info here: clinicaltrials.gov/study/NCT06684… Tor Biering-Sørensen, MD, MSc, MPH, PhD CTCPR Trials & CIRL

Teaching the next generation of doctors in Cardiovascular Pharmacology 🫀💊📚 Tor Biering-Sørensen, MD, MSc, MPH, PhD CTCPR Trials & CIRL University of Copenhagen

🚨 DAN-RSV trial update 🚨 During the first week of inclusion, we have managed to individually randomize more than 50000 Danish citizens! DAN-RSV will provide unique information on whether a RSV vaccine can prevent hospitalizations. Please read more about our trial below 👇

Update on the DAN-RSV trial 🚨🦠🚨 After 1 week of recruitment we have managed to individually randomize 50.000 participants 1:1 to the RSVpreF vaccine 💉 or no RSV vaccine 🚫💉! Read more about the trial here: clinicaltrials.gov/study/NCT06684… Tor Biering-Sørensen, MD, MSc, MPH, PhD CTCPR Trials & CIRL

🚨 DAN-RSV trial update 🚨 During the first 2 weeks of inclusion, we have individually randomized > 100.000 Danish citizens! CTCPR Trials & CIRL is yet again revolutionizing how to generate the highest level of evidence by embedding prospective randomization within nationwide registries 👇

Our most recent publication from the NUDGE-FLU trial program (the NUDGE-FLU-CHRONIC trial) out in JAMA 👇 We report the highest increase in vaccine uptake ever reported in an implementation trial CTCPR Trials & CIRL Niklas Dyrby Johansen Muthu Vaduganathan Ankeet S. Bhatt, MD, MBA Kaiser Permanente Research NorCal Brigham and Women's Hospital

Excited to kick off day 1 of our annual RCT course at Københavns Uni with Danish Cardiovascular Academy! Caroline Espersen Manan Pareek, MD, MSc, PhD, FAHA, FESC Maria Dons & Niklas Dyrby Johansen will take us through RCT fundamentals and we'll conclude with a trial stats📊masterclass by Brian Claggett from Harvard Medical School Tor Biering-Sørensen, MD, MSc, MPH, PhD

Thank you to د.محمد بلغيث البارقي and the #RSH2025 organising committee for inviting me to be part of the faculty at this year’s excellent meeting. It was an absolute pleasure to contribute. A truly outstanding event!

It was a great honor to participate in yet another Duke Clinical Research Institute think tank meeting lead by Adrian “WE NEED RCTS!” Hernandez, Kanecia Zimmerman and Derek Angus. This time on the very important topic of Platform Trials. The whole event was initiated by the former FDA Commissioner Dr. Robert M. Califf CTCPR Trials & CIRL

👏 Amazing achievement Adam Femerling and the rest of our COLFIB team! We are well on the way towards the goal of 500 patients randomized in the COLFIB trial, where we are assessing whether colchicine can be used to prevent AF recurrence. CTCPR Trials & CIRL UCPH Healthscience

To be presented at #ACC25 JACC Journals in Chicago next week! Our study showing 4-8 times ⬆️ incidence of CV🫀events following acute infection with RSV 🦠 using national 🇩🇰 test data: jacc.org/digital-conten… Tor Biering-Sørensen, MD, MSc, MPH, PhD Niklas Dyrby Johansen

Read this interesting work from my colleague Maria Dons regarding Hidradenitis Suppurativa and Cardiovascular Risk! 🫀📝🌟

Wonder what makes #healthcare systems successful? Read this 📑 on #Denmark led by Tor Biering-Sørensen, MD, MSc, MPH, PhD in #GlobalRounds Circulation Economically just society Universal healthcare Strong primary care for every person Enviable clinical & research infrastructure ahajournals.org/doi/full/10.11…

📢 New Publication. This review highlights #psoriasis as an independent risk factor for #cardiovascular disease. A coordinated multidisciplinary approach, early counseling on CVD risk & heart-healthy lifestyle are key! Learn more: journals.lww.com/co-rheumatolog…

🚨New publication alert in EJHF Editor-in-Chief Collaborative effort across cardiology and hepatology Key Findings 1️⃣18% of patients with biopsy-proven MASLD developed HF➡️ HFpEF 2️⃣50% met criteria for suspicion of HF 3️⃣Risk was highest among older adults, women, and those with diabetes

Rationale and design of NUDGE-CKD: A nationwide randomized factorial trial of electronic nudges for increasing guideline-directed medical therapy in CKD #ERA25 Evaluating if a single electronic letter can increase GDMT use in patients with CKD. sciencedirect.com/science/articl…

Will be very interesting to see the results of the NUDGE-CKD trial soon! 👀📝 Kristoffer Grundtvig Skaarup Niklas Dyrby Johansen

#NUDGECKD in Circulation #ERA25 by Kristoffer Grundtvig Skaarup & Tor Biering-Sørensen, MD, MSc, MPH, PhD Nationwide 2x2 Pragmatic Implementation Mega-Trial 👥 n=22,617 🇩🇰 adults w #CKD 🥼n=1540 General practitioners Electronic nudges did not improve uptake of #RASi or #SGLT2i versus usual care ahajournals.org/doi/10.1161/CI…