Fabrizio Fierro
@fabrizio_fierro
Structural bioinformatician mainly focused on receptor/ligand interaction (GPCRs, TAS2Rs, drug discovery, MD, homology modelling, ...) #NivLab #HebrewUniversity
ID: 3495718341
30-08-2015 23:10:43
26 Tweet
161 Followers
474 Following
There’s An Unexpected Loss Of Smell And Taste In Coronavirus Patients forbes.com/sites/judyston… please RT Asaf Ronel השולחן של נדב make sure to self isolate if smell/taste lost Thanks Paule Joseph, PhD, MBA, CRNP, FAAN for sharing!
Thank you! Honoured to chair a session of the second Ernest meeting TasteLabHUJI #ERNEST_COVID19 ERNEST - A Research Network on Signal Transduction
Session 7 of the second Ernest meeting live now! Me and TasteLabHUJI chairing this session. ERNEST - A Research Network on Signal Transduction #gpcr
Il questionario del @GCChemosensoryR adesso è disponibile in italiano! #GCCR survey in Italian! Please RT!
CASP14 #s just came out and they’re astounding—DeepMind looks to have solved protein structure prediction. Median GDT_TS went from 68.5 (CASP13) to 92.4!!!! Cf. their 2nd best CASP13 struct scored 92.8 (out of 100). Median RMSD is 2.1Å. I think it's over predictioncenter.org/casp14/zscores…
Wonderful collaboration with colleagues in Japan "Lowered sensitivity of bitter taste receptors to β-glucosides in bamboo lemurs: an instance of parallel and adaptive functional decline in TAS2R16?" royalsocietypublishing.org/doi/10.1098/rs… congrats to Fabrizio Fierro !
Cryo-EM structure of the human MC4R-Gs signaling complex bound to the agonist setmelanotide, a cyclic peptide approved for the treatment of obesity. Hats off to The Shalev-Benami Lab, so happy to collaborate! Well done Fabrizio Fierro! science.sciencemag.org/content/early/…
Now out on Science Magazine! CryoEM active structure of MC4R and its activation mechanism uncovered. Superb work by Hadar Israeli 🦋, Oksana Degtjarik, The Shalev-Benami Lab, and all the team members! TasteLabHUJI lab contribution summarized in the video!⬇️ t.ly/uYIP
Happy moment at ECRO 2022 - Berlin - lab #alumna Antonella Di Pizio is handling questions addressed to Fabrizio Fierro, after he presented his #bitter #antagonists talk. Wonderfuly #ECRO2022 overall, and Sebastien Fiorucci and @LSB_dipizio_lab symposium in particular!
Discovery of 2-Aminopyrimidines as Potent Agonists for the Bitter Taste Receptor TAS2R14 pubs.acs.org/doi/10.1021/ac… - Great collaboration with Gmeiner Group! Congratulations ⌬ Lukas Waterloo ⌬ , well done Fabrizio Fierro !
A major part of my PhD work has recently been published in J Med Chem! Thanks to my former colleagues at Gmeiner Group, TasteLabHUJI and Fabrizio Fierro without which this work wouldn't have been possible!