Great example of material loss from tibial tray. The poly insert has even managed to imprint its catalogue number.... Just to emphasise - this is not material/device specific. Do consider ARMD in #totalkneereplacements #arthroplasty with unexplained pain explantlab.com/orthotype-test

We’ve just had an #arthroplasty paper put online in The Knee, official journal of @baskonline “Aseptic Loosening of the Option Stemmed Tibial Tray in the Zimmer NexGen LPS Total Knee Arthroplasty System.” Below is link for temporary free access authors.elsevier.com/c/1iMP83S6VBC1…

Unexplained pain post #arthroplasty Could it be due to adverse reaction to metal debris? This is determined by metal exposure and genetics. New test available on NHS combines ICPMS metal levels + genotyping. OrthoTweets OrthoTwiter hospital.blood.co.uk/diagnostic-ser…

#Unicompartmental knee analysis looking good now. Key findings so far: 1. Volumetric poly wear of explanted unis is 1.5 > than in total #kneearthroplasty (why?!) 2. Backside surfaces show wear (red), rather than the deformation we tend to see with contemporary #TKR

ncbi.nlm.nih.gov/pmc/articles/P… Another study, another group showing ALVAL rates around 30% in failed #tkrs ALVAL is clearly a major contributor to unexplained pain. When is the orthopaedic community going to start discussing this properly? Chloe EH Scott Exeter Knee Reconstruction Unit Christopher Pelt, MD Lee E. Rubin, M.D., FAAOS, FAAHKS, FAOA

Nasty looking explanted RP tray revised for pain, tibial bone loss.

Our Innovate UK funded @nhs study is showing some important results for patients with #jointreplacements. The “Arthrogenex”study examines #arthroplasty #genetics and explants. It is clear that metal release in TKRs is important. Get in touch if you would like to take part.

Bloody immigrants, coming over here, stopping our kids from being stabbed…

This will be a really interesting event. Jeremy Latham will be talking too. Some of the talks will be dynamite. Surgeon, patient, engineering, legal aspects all to be discussed, everyone welcome. And Newcastle is a great place to visit.

Some nice early results from our Arthrogenex study. Titanium concentrations in patients with nexgen LPS TKRs attending review clinics at 4 to 10 year follow up. Correlation coefficient-0.7, p=0.002 Funding in place for 1750 patients, outcome scores, blood metal ions and genetics.

We will present latest results of NHS study on genetics+metal ion levels in painful knees @ personalized arthroplasty meeting next month, Chicago. We have 4 UK sites and 2 international actively recruiting, study in set up at 4 others. Mark Bowditch would yr unit be interested?