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A beginner’s guide to assembling a draft genome and analyzing structural variants with long-read sequencing technologies sciencedirect.com/science/articl…

Legend Theo Meuwissen presents an elegant analysis to show including causal variants improves genomic prediction accuracy WCGALP2022 #WCGALP2022

We've made a draft human pangenome! 47 haplotype-resolved assemblies, two reference genomes, and five pangenome graphs!

"For many decades claims have been made that quantitative genetics was dead or dying but, condescendingly, perhaps still useful until the contents of the black box were revealed, a feat which would be ‘just round the corner’. " - William G. Hill nature.com/articles/s4158…

‼️ ONLINE NOW Nature Genetics 📰 A multi-tissue atlas of regulatory variants in cattle 🧑🏾‍🤝‍🧑🏼 George E. Liu Albert Tenesa Lingzhao Fang and team ⬇️🐄⬇️ go.nature.com/3vTfLyn

This is a great moment for the FarmGTEx project. Our pilot CattleGTEx work is online in Nature Genetics now. The new phase of CattleGTEx is starting now. Please contact if you are interested in. Together we build a comphensive FarmGTEx atlas!

Congratulations Lingzhao Fang and the whole team! 🐄

A multi-tissue atlas of regulatory variants in cattle. #CattleRegulatoryVariants #TissueVariantAtlas #CattleGTEx Tenesa Group Lingzhao Fang Nature Genetics nature.com/articles/s4158…

nature.com/articles/s4158…

Yao, Liu, Charley Xia, Gao, Pan, Liu, Lingzhao Fang, Albert Tenesa & co compare the transcriptomes of human and cattle from 20 tissues. Much about expression, including eQTLs, are conserved between the species. Heritability is higher for conserved genes genomebiology.biomedcentral.com/articles/10.11…

How cool is that, the CattleGTEx paper has made the Nature Genetics cover😎. Current issue contains both, research briefing on paper and FarmGTEx 🧑‍🌾🧬🐄🐷🐔more broadly (nature.com/articles/s4158…) and the paper itself (nature.com/articles/s4158…)

It is soooo cool to see that the CattleGTEx made Nature Genetics Cover! Welcome to join the next phase of CattleGTEx. Please contact [email protected] for more details. The FarmGTEx website (farmgtex.org) will be online soon.

A compendium of genetic regulatory effects across pig tissues biorxiv.org/cgi/content/sh… #bioRxiv

A compendium of genetic regulatory effects across pig tissues biorxiv.org/cgi/content/sh… #biorxiv_genomic

I am so thrilled to share our PigGTEx resource, as part of the FarmGTEx project. Here we provide the first comprehensive atlas of regulatory variants (e.g., eQTL) across 34 tissues in pigs, and show its importance in studying complex trait genetics and human biomedicine.

The🐷GTEx is here. Regulatory variants (eQTLs, sQTLs and more) across 34 tissues in pigs and lots of follow-on analyses. Great work from the FarmGTEx consortium led by Lingzhao Fang.

If you like this one you might also like the earlier work on the 🐄GTEx published earlier this year nature.com/articles/s4158…