Preprint on "BWT construction and search at the terabase scale". We can compress 100 human genomes to 11GB in 21 hours, find SMEMs with it, do affine-gap alignment and retrieve similar local haplotypes. 7.3Tb commonly sequenced bacterial genomes ⇒ 30GB arxiv.org/abs/2409.00613

Heng is like the Messi of bioinformatics. Absolute legend!

Still time until 15th September to submit an abstract to join us in Berlin in the European Society for Spatial Biology conference 👇

What He did was a crime. Which is why he went to jail for it. He experimented on two/three embryos, failed by his own criteria, and brought those embryos to term. He violated every bioethical code, not as a medical intervention but for a prophylactic.

Congratulations, Nicoletta Petridou! 👏 The EMBL Group Leader has received an ERC Starting Grant. CoRe – the funded project – aims to use physics to develop synthetic developmental biology tools to study tissue physical properties in living embryos. embl.org/news/awards-ho…

Our new breast cancer germline gene meta-analysis just published in Annals of Oncology compares and combines UKBiobank, BRIDGES and CARRIERS datasets: in total 101,397 unselected ‘population-type’ female breast cancer cases and 312,944 controls. Association and variant frequency

Locational pricing- not just a workaround for islands, but a solution for the whole nation Stop paying generators to turn off ZERO MARGINAL COST power, and instead sell it locally cheaply Locational pricing means we'd build what we need where we need it & cut bills for everyone

I'm afraid this week the standard (bifacial PERC) solar module price fell to $0.095/W. What a world we live in.

Ewan Birney Thank you for the kind words, and thanks EBI for hosting this huge dataset and making it available for the community! ebi.ac.uk/empiar/EMPIAR-…

Check out our new work led by Daniel Malawsky on common and rare variant contributions to longitudinal measures of cognitive ability, using new exome sequence data from British birth cohorts. Lots of interesting findings about dynamic and non-uniform effects of genetics on cognition.

🧬 The GA4GH 12th Plenary is just a few days away! 🌍 We highly recommend checking out the speaker lineup, containing many of the leading voices in #genomicmedicine! 👉 Register here: broadinstitute.swoogo.com/ga4gh-12th-ple… ✨ #GA4GHPlenary #Genomics

ok - long term Oz/UK commuters (Mike Inouye, Daniel MacArthur, Lachlan Coin others...) - what is the "best" pattern for sleep/melontin usage/other tricks of the trade to minimise bamboozling jet lag on UK->AUS and AUS->UK return?