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A nice plenary talk from Evgeny Kvon at #2024SDB. Learn more about Evgeny's work on enhancer biology in this 'Transitions in development' interview for Development. doi.org/10.1242/dev.20…

Ken is more than Kenough! #2024SDB was a FANTASTIC meeting! Hope to see you all in Puerto Rico for #2025SDB !!!

Made sure the lab is well-caffeinated.

Penn's Department of Genetics has several new tenure-track assistant professor openings. Please help spread the word! apply.interfolio.com/147616

(1/16) Check out our Simon Gaudin paper tiny.cc/icuazz from the Canzio lab out in Science Magazine today on how tuning local cohesin trajectories enables differential readout of the clustered Protocadherin (Pcdh) locus across different types of neurons.

A heads up to all post-docs - the Genome Biology dept @EMBL is recruiting - independent group leader (PI) position. Outstanding colleagues, students, world-leading core facilities in a very supportive, collaborative and family environment, #jobs. Ad will be posted in next days

Fresh PhD Student 5th year Postdoc #AcademicChatter PhD Voice - Independently Run

The academic job market in the good ol' days vs the academic job market today.

Very proud to have contributed to the #lungfish genome project! Most Lepidosiren’s chromosomes are larger than the human genome! nature.com/articles/s4158…

Loss of ETS sites in the ZRS enhancer of Shh has been linked to limb reduction in snakes. Here is another example of independent ETS site mutations in the ZRS linked to fin reduction in some lungfishes. Congrats to all authors of this tour de force study! nature.com/articles/s4158…

As we head into the new school year, if you're an intro genetics instructor and would like to share exams, slides, problem sets, activities, and other teaching materials, you're invited to join the Genetics Educators Exchange. Please request access here: forms.gle/535PnGhBbJU7ig…

Our preprint describing how #developmental genes and #CTCF clusters cooperate in the robust #insulation of regulatory #domains just got published in Nature Communications rdcu.be/dRMcN

We present The Transcription Factor Binding Landscape of Mouse Development🐭🧬 #DevBio We use CUT&RUN-LoV-U to map Many SignalingPathways X 4tissue X 2stages It is a huge dataset - yet only the beginning of the TranscriptionFactorBinding(TFB)-OMICS biorxiv.org/content/10.110…

This is a fascinating article about the discovery of the first transcriptional activator gene. Jacob, Monod and others were skeptical of the positive control model. Of course today we know that it's much more widely used mechanism than repression. dx.doi.org/10.1534/geneti…

It is challenging to study the ability of transcription factors to engage their motifs in the cell. We tried to address this in our new study together with Marco (Marco Pregnolato), Schübeler Lab, and FMI science: cell.com/molecular-cell…

New preprint by our lab -- Revealing the functional landscape of a large genomic locus by highly multiplexed local hopping of a reporter: biorxiv.org/content/10.110…. Even a 'simple' genomic locus such as the mouse Sox2 locus still holds surprises...

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Our department is recruiting a faculty member! A great position in a well-supported environment!! Please apply by 10/31. recruit.ap.uci.edu/JPF09237

In The Scientist Digest, Assistant Professor Evgeny Kvon explores how enhancers, which are non-coding regulatory DNA elements, orchestrate the precise spatiotemporal transcription of genes during mammalian development: bit.ly/3yXuuNR Evgeny Kvon

Enhancers have piqued the interest of researchers since their discovery in the early 1980s. In his lab UC Irvine, geneticist Evgeny Kvon studies how they regulate gene expression during mammalian development. Learn more in this interview: bit.ly/3MtvoES