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#WhatsNewOnFMT #ECCO24 FMT in UC ➡️ RESTORE-UC trial randomised controlled trial = stopped for futility! Allogenic FMT (n=30) Autologous FMT (n=36) 10% vs. 13% response rate! Primary response was associated with lower Mayo score! doi.org/10.1093/ecco-j…

rdcu.be/dzX6K ; Studying 87 patients, FMT induced changes in the recipient resistome associated with a reduction in the abundance of Enterobacterales. However, specific recipient-ARGs persisted mainly located on plasmids. EurFMT Wiep Klaas Smits Nicolas Benech

#WhatsNewOnFMT #ChronicPouchitis Meta-analysis ➡️ high heterogeneity among studies and still limited evidence for the use in clinical practice. 👉Need for randomized placebo-controlled trials! doi.org/10.1093/ecco-j… EurFMT

Follow our #EurFMT newsletter! Issue No. 5, March 2024 The regulatory landscape that frames microbiome therapies in Europe is evolving, and clinical data emerge. Here is your quarterly update on intestinal microbiota for therapeutic application. 👉mailchi.mp/beb584558436/e…

"Wine matures with age" 👉but what about Faeces? ... may be in relation to immunotherapy effectivity... ➡️Older cancer patients show enhanced response to immunotherapy ➡️Aging-enriched enterotypes correlate with improved outcomes in ICB treatment, and #FMT enhances response to

#WhatsNewOnFMT What is the role of bezlotoxumab in #FMT for C.difficile in #IBD patients? No benefit, but likely with more patients included/power it is possible that bezlotoxumab would even reduce efficacy and be associated with a higher rate of recurrence... 👉So if you are

Pleased to finally see the new BSG Healthcare Infection Society #FMT guidelines out today, a great team effort that we hope will improve access to safe and effective use of this therapy: doi.org/10.1016/j.jhin… Metabolism, Digestion & Reproduction Imperial Hepatology NIHR Imperial BRC EurFMT

Now swiftly followed by the Gut Journal version, online now: gut.bmj.com/content/early/… BSG Healthcare Infection Society Imperial Hepatology Metabolism, Digestion & Reproduction EurFMT NIHR Imperial BRC Infection & AMR

#WhatsNewOnFMT Mixed donor FMT vs. single donor FMT mFMT: 13.2% achieved ≥10% weight loss sFMT: 0% achieved ≥10% weight loss ✔️Mixed-donor FMT was associated with increased butyrate-producing bacteria for obesity gut.bmj.com/content/73/5/8… Siew Ng Francis Chan MD Gut Journal

Don't forget to submit your abstract for the annual meeting of the European Helicobacter and Microbiota Socienty Group #EHMSG! ⌛️Deadline: 6 May 2024! 👉workshop.ehmsg.org

Fecal microbiota transplantation for recurrent C. difficile infection can be the best therapeutic option in severely immunocompromised patients depending on a case-by-case assessment of the benefit/risk ratio ⁦Gastroenterology⁩ sciencedirect.com/science/articl…

New review alert: Fecal microbiota transplantation: current challenges and future landscapes journals.asm.org/doi/10.1128/cm… - thanks to Babak Yadegar and Dina Kao for bringing this work to completion! CC Ed Kuijper Gianluca Ianiro EurFMT Giovanni Cammarota Tanya Monaghan

Today, 13.05.2024, the first virtual general assembly of the EurFMT meeting 👉Current status 👉Ongoing projects/applications 👉Invited Interaction with Industry 👉New EU FMT regulations (SoHo) Really excellent interaction and discussion!

#WhatsNewOnFMT in #LiverCirrhosis Phase 2 data on FMT in patients with hepatic encephalopathy 👉Recurrence of HE was significantly lower with FMT compared to placebo 👉Reduced hospitalization rate 👉Donor-independent effect 👉Oral vs. enema vs. both = similar effect Excellent

Excited to present our data @ #IHMC2024 on FMT to tackle #AMR in cirrhosis, we see restoration of gut barrier function/immunity, immunometabolisim & with collaboration with Phase Genomics we see beneficial bacteriophage remodelling !

#WhatsNewOnFMT in children with constipation Randomized, double-blind, controlled trial Enema+Placebo vs. Enema +FMT ✅FMT enhances the efficacy of colonic enema and the use of enema-based FMT is a safe and effective method in the treatment of intractable constipation in

Join us at the 37th Workshop of the European Helicobacter and Microbiota Study Group (#EHMSG) held in Porto, Portugal on September 12 - 14, 2024 workshop.ehmsg.org/registration

4th General Assembly #EurFMT October 12, 2024 in Vienna Topic: FMT landscape in EU, SoHo regulation etc. If you are interested in attending the meeting - there are only a few places left! Please use the email pre-registration 👇!

EHMSG - an excellent opportunity for interaction and networking on microbiota, FMT, Helicobacter infection, gastric cancer and much more! It was great to catch up with friends and colleagues in Porto!

Amazing to see such a great participation and interaction at the #EurFMT General Assembly in Vienna during #UEGWeek 2024!