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⛴️ On my way to Turku, Finland 🇫🇮, for #ECCB2024 ECCB2026 Geneva, Switzerland. If you want to learn about figeno, my visualization too for genomic data 🎨🧬 (github.com/CompEpigen/fig…), come to my talk at #ESCS2024 ESCS2024 tomorrow at 11:15, and to my poster (P15) on Wednesday at 6:30pm!

My poster for figeno (P15) is up at #ECCB2024 and I will present it this evening! Check it out if you want to visualize Oxford Nanopore, HiC, bigwig or WGS data! If you have already used figeno, I'd love to hear your feedback and suggestions for improvements. github.com/CompEpigen/fig…

Contributing to tour de force led by Reka Toth Reka Toth Reka Toth and Pavlo Lutsik Pavlo Lutsik from LIH_Luxembourg KU Leuven DKFZ comparing #computational workflows for processing DNA #methylation sequencing data. Called "Pipeline Olympics" is available at bioRxiv

How are promoter interactions coordinated during cell differentiation? In our first paper, we investigate the temporal relationship between genome folding, transcription and histone modifications during ESC differentiation. (1)

A man with a therapy-associated NPM1-mutated acute myeloid leukemia. How single-cell DNA sequencing reveals a complex clonal evolution. haematologica.org/article/view/h…

EpiCHAOS: a metric to quantify epigenomic heterogeneity in single-cell data genomebiology.biomedcentral.com/articles/10.11…

An article published in Genome Biology presents epiCHAOS: a quantitative metric of cell-to-cell heterogeneity, applicable to any single-cell epigenomics data type. genomebiology.biomedcentral.com/articles/10.11…

1/n UV radiation disrupts genome integrity, but how does the 3D genome facilitate DNA damage response (DDR)? Our latest study with Ogulcan reveals how UV-induced genome reorganization enables efficient repair. 🌟🔬 🔗 nature.com/articles/s4146…

Thrilled to share our latest research! Our manuscript on CHD1L’s role in neurodevelopment and its implications in 1q21.1 syndromes is now on BioRxiv! 🧬🐟🧠 🔬 Read our findings here: doi.org/10.1101/2025.0… #Neurodevelopment #1q21 #Zebrafish #hiPSC #Autism IGBMC

Two tools for plotting genomics data: figeno: Tool for making genomics figures in #python. github.com/CompEpigen/fig…

Enhancer hijacking discovery in acute myeloid leukemia by pyjacker identifies MNX1 activation via deletion 7q: brnw.ch/21wRWqT

Our work on aberrant MNX1 expression in AML caused by enhancer hijacking is finally out! Great collaboration between the Plass lab, Translational Cancer Epigenomics and many others! Thanks a lot to everyone involved! 🙋🏻‍♂️

Online First: Enhancer Hijacking Discovery in Acute Myeloid Leukemia by Pyjacker Identifies MNX1 Activation via Deletion 7q brnw.ch/21wTmf1