Today marks the 25th anniversary of Neil Risch and Kathleen Merikangas' classic 2-page paper that articulated GWAS as the future of human genetics. A short thread. www-leland.stanford.edu/~huatang/gene2…

Thank you to the scientific community for all of the interest on our paper! Our new partnership with the CDC will further study the role of #humangenetics in #vaccineeffectiveness as we examine ~10K patients w/ breakthrough infections + severe COVID, despite full vaccination

Interesting idea: "Identification and analysis of individuals who deviate from their genetically-predicted phenotype" biorxiv.org/content/10.110…

Nice work! Great to see this resource.

Combining rare and common genetic variants improves population risk stratification for breast cancer medrxiv.org/cgi/content/sh… #medRxiv

Congrats Ryan Dhindsa Slavé Petrovski great to see this work!

What a lovely graph

Excited for Natalie’s talk today at #ASHG2023 and her accompanying preprint showing that kidney disease in PKD1 and PKD2 carriers can be predicted 11 years ahead of time with a PPV of 71% medrxiv.org/content/10.110…

Our latest study is live on medRxiv medrxiv.org/content/10.110… We asked why some (unvaccinated) individuals remain asymptomatic after SARS-CoV-2 infection, using 3 large cohorts. And learned a lot on HLA & role in chronic phase of infection vs. acute phase Check 🧵

Congrats to Alexandre Bolze and coauthors on research demonstrating how personalized genetics can help defer breast cancer screening for those at low risk. Read the feature on GenomeWeb: genomeweb.com/sequencing/bre…

Lovely study, glad to see this write up!

Helix's latest preprint on COVID vax protection against severe illness during 2023-24 respiratory season. Highlights: - XBB.1.5-based booster provided add'l protection over the 2023 booster - Potentially lower XBB.1.5 mRNA vaccine protection against JN.1 vs XBB variants

🚨 New from Liz Cirulli & colleagues 📰 A power-based sliding window approach to evaluate the clinical impact of rare genetic variants in the nucleotide sequence or the spatial position of the folded protein 👉bit.ly/43sSxPj

Were you diagnosed with #myocarditis following a #Covid #vaccine or illness? Participate in study Helix is conducting. Find out more here: myocarditisfoundation.org/participate-in…

Helix is presenting 4 talks at ASHG this year, with the first starting in a few minutes. Come see our scientists present their work! #ASHG24 #ASHG2024 helix.com/events/ashg2024

I’m so excited to try this out!

#InTheNews: Welcome TriHealth, Parkview Health & Rochester Regional Health to the Helix Research Network! Together, we’re adding 300K participants to the world's largest and fastest-growing clinical research network to drive early detection and prevention. bit.ly/4ahzniG

Great talk ACMG #ACMGMtg25 by Dr. Chad Haldeman-Englert discussing Cone Health GeneConnect program & the Helix Research Network. Benefits to sequencing all adults to keep population healthy. cc Helix

Curious about the impact of population genomic screening on LDL-C levels? Matt Levy gave a great talk at #ACMGMtg25 Check the manuscript below. And feel free to email with Qs. ACMG Helix

Great time at #ACMGMtg25! Grateful for all who came to our booth, talks & posters—plus the highlight from Michael Murray (Mount Sinai Institute for Genomic Health) at the final symposium. Proud to partner with so many leading health systems to make genotype-first care a reality #genomics #precisionhealth