Incredible scenes of a killer T-cell destroying an ovarian cancer cell many times its size 👾💥

Windows XP vibe wasn’t appreciated enough

The Information Theory of Aging (ITOA) posits that epigenetic noise expressed as Shannon’s entropy is a cause of aging. Cheek DNA methylation noise is shown to predict chronological age, consistent with ITOA. Is it reversible?

I actually celebrate aging today

I had to try it 🙂‍↕️

The mitochondria

open.substack.com/pub/maxmarkovi… Very interesting piece from my colleague and friend

I can't get over these 3D spatial images in the latest preprint from Peter Sorger Ajit Johnson Nirmal et al. The preprint is a roadmap on how to conduct 3D cyclic immunofluorescence using "thick" archival sections and precisely map cell-cell interactions biorxiv.org/content/10.110…

Looking forward to the post-genomics era of cancer research. What’s it going to be? journals.plos.org/plosbiology/ar…

GPT-4-draft-35_ME, GPT-4_final_FINAL, GPT-4_submission

Making sure I get enough sun and caffeine

3 coffees no lunch

🚨 Just released by National Cancer Institute Annual Report to the Nation 2025: Overall Cancer Statistics Most cancers in both men and women showed decreases in mortality. The incidence rates for certain cancers including #PancreaticCancer (and bile duct cancers in women) saw increases. Details:

Reminds me of blackberry I had long time ago 🥹

Everybody in spatial biology knows that we already have codex

That’s really something I am excited about 🤩

It’s been a few years since my last western blot, but the trauma is still there 😅

Short piece in EACR magazine about my stay at Laboratory of Systems Pharmacology @HarvardMedical. Miss my time in Boston so much 🙌🏻🤍 magazine.eacr.org/mikhail-ermako…

That's exactly what I love about biomedical sciences training - it teaches you experimental intuition, which you try to apply everywhere, and only then numbers come into play