Excited to co-organize the virtual EACR Boehringer Ingelheim Conference: Drugging & Regulating the MAP Kinase Pathway! Submit an abstract or join us. Please RT and share with others. Details & registration: eacr.org/conference/boe…

Today we report in Nature Genetics the genetic landscape of cancer drug resistance mechanisms from CRISPR base editing screens nature.com/articles/s4158…

Thrilled to share our paper now out nature delineating #plasticity during #CRC #metastasis, a fantastic collaboration led by Andrew Moorman Ellie Benitez, and @f_cambuli from the Karuna Ganesh Lab and @dana_per lab! nature.com/articles/s4158… rdcu.be/dYAVK. A 🧵

Great post-doc opportunity👇🏽

Love this photo, perhaps the most rewarding part of my job is nurturing talent and seeing it flourish.

Couldn't agree more - what a great meeting and group of people.

Adapmet is an amazing consortium working on cancer and metastasis and offers PhD positions. If you want to perform a PhD in these topics (either in academia or industry), please apply for these positions through the website interface before January 9th. Please forward the post!

Several years in the making (and aging), Xueqian Zhuang 's study on aging is out today nature. She finds, surprisingly, that aging suppresses tumorigenesis and stemness in the lung by promoting a functional iron insufficiency in the alveolar epithelium. nature.com/articles/s4158…

📢Very excited to share this paper with you! The oestrous cycle stage affects mammary tumour sensitivity to chemotherapy published nature . Congratulations to Laura, Colinda Scheele and all the authors for this amazing story. nature.com/articles/s4158…

Nice summary of some key discoveries published over the last 12 months

New paper from the lab🎈. Introducing Micro Immune Response On-chip (MIRO), a device that replicates tumors and their microenvironment to better understand responses to immunotherapies (cyan=immune cells, red=cancer, green=CAFs). IBEC

Delighted to have contributed to this interesting set of perspectives on bridging gaps between fundamental and clinical research cell.com/cancer-cell/fu…

Excited to share details of this meeting and the exciting line up of speakers. Hope to see you there. Please re-post crick.ac.uk/whats-on/5th-c…

Thought provoking new study from the Sixt and Hannezo groups - the texture of the environment impacts collective vs single cell cancer invasion biorxiv.org/content/10.110…

Synthetic biology could enable new types of programmable therapeutics. Our new preprint introduces synthetic protein circuits that selectively trigger cell death in Ras-mutant cancer cells, with interesting advantages compared to existing approaches. biorxiv.org/content/10.110…

Really neat study applying new ML methods to our Alix Le Marois imaging data to predict the fate of lung cancer cells following EGFR inhibition. biorxiv.org/content/10.110… see also biorxiv.org/content/10.110…

Many congratulations Will, richly deserved. Looking forward to following your progress.

Excited to share our new study on how resistance to AKT inhibition is linked to lineage differences within breast cancer 👇🏽biorxiv.org/content/10.110… and also surprisingly/worryingly good AI generated podcast 🎧notebooklm.google.com/notebook/28ebc…

I love this work!

Proud to share our new nature study: We developed the 1st NNMT inhibitor that reprograms cancer-associated fibroblasts, boosting immune response & stopping tumor growth in ovarian cancer models, especially when paired with immunotherapy. Lengyel Lab nature.com/articles/s4158…