I am thrilled to say that our last work was recently published. Mike dos Santos 's first one! We show the activity of the MMV Pandemic box against #Toxoplasma . We found 19 new active compounds against the tachyzoite stage of this parasite. mdpi.com/2581876 Sociedade Brasileira de Protozoolgia

Our lab has a fully funded PhD position opening up to work on a very exciting project co-led by @paulafaral and myself, on apicomplexan reactivation. Starting date can be convened between May and August 2024. Apply before Jan 10th. DM me for further details and pls RT.

Maria E. Francia (she/her) @paulafaral Please share the details

Mariana Silva, Andrew Maclean and colleagues show that a critical metabolic enzyme (#ComplexII) of the parasites causing #toxoplasmosis has many more parts than its human parallel - another nail in the parasites are "reduced" / 'simple" coffin. journals.plos.org/plospathogens/…

Wow

Congratulations 🥳 for HAMZA Elati, 🇱🇾 first paper, and thank you to bm Harry De Koning for inviting us to join this nice collaboration frontiersin.org/articles/10.33…

📚Findings in the fight against Toxoplasma gondii! 💊 Explore the Medicines for Malaria Venture Pandemic Box In Vitro Screening, identifying compounds highly active against the Tachyzoite Stage. Read the full paper here: mdpi.com/2414-6366/8/12…

A study of how the critical #nucleus and #mitochondrion interact, performed in the protozoan parasite #Toxoplasma, reveals a contact mediated by abundant & ubiquitous complexes in their membranes. #TOM #NuclearPore hubs.la/Q02nKSMQ0 @sheinerlab UofG Sii Mathieu Gissot

A study in Journal of Cell Biology of how the critical #nucleus & #mitochondrion interact, performed in the protozoan parasite #Toxoplasma, reveals a contact mediated by abundant & ubiquitous complexes in their membranes #TOM #NuclearPore hubs.la/Q02nL0m90 @sheinerlab UofG Sii Mathieu Gissot

Our first stab at finding routes of communication between the #nucleus and the #mitochondrion in #Toxoplasma discovered #contacts between the mitochondrion and the nuclear pore. doi.org/10.1083/jcb.20…

Nuclear-mitochondrion contacts functions are not known. Cell adaptation to stress(1) and for drug resistance in #malaria(2) was proposed. But we are still exploring what is the role of the contact we just reported - stay tuned! 1 science.org/doi/10.1126/sc… 2 pubmed.ncbi.nlm.nih.gov/34044591/

I'm really happy to have collaborated in this beautiful work.

Two ancient membrane pores mediate mitochondrial-nucleus membrane contact sites, say Jana Ovciarikova (Jana), Lilach Sheiner @sheinerlab UofG Sii & colleagues: hubs.la/Q02n_1jJ0 Shikha Alice Lacombe Leandro Lemgruber Erica Martins Duarte Mathieu Gissot Andrew Maclean

Se os 3 mil bilionários do planeta pagassem 2% de impostos sobre o rendimento das suas fortunas, poderíamos gerar recursos suficientes para alimentar as 340 milhões de pessoas que, segundo a FAO, enfrentam insegurança alimentar severa na África. Muitos países em desenvolvimento

Almost arriving in Berlin for Toxo Meeting 2024.

It is confirmed! Next Toxo Meeting will be in Brazil 🇧🇷🇧🇷🇧🇷

For more information follow Toxo18 Brasil

Our newest work is out! Investigation of Virulence-Related Markers in Atypical Strains of Toxoplasma gondii from Brazil mdpi.com/3159994 #mdpimicroorganisms via Microorganisms MDPI

SAVE THE DATES: June 14-17 2026, at Hotel Atlântico Buzios, Armação de Búzios, Rio de Janeiro, Brazil!

I'm editing a new special issue for Microorganisms MDPI Original and review papers focused on parasitic infections are welcome