We are excited to share our lab’s first research article! rdcu.be/dU5AC We have developed Transferrin Receptor Targeting Chimeras (TransTACs), a novel class of heterobispecific antibodies designed for targeted degradation of membrane proteins. nature.com/articles/s4158…

Just experienced an amazing morning of science and clinical research at the Desai Sethi Urology Institute research retreat Miller Medicine! Incredible colleagues and energy here! sanoj punnen Raveen Syan, MD, FPMRS Katie Amin, MD, FRCSC Zhipeng A. Wang Pedro F. S. Freitas, MD Dipen J Parekh, M.D.

An amazing first experience at the DSUI research retreat with all the institute peers, admins, and my team! Gave a short talk and felt the excitement of collaboration. Looking forward to bridging basic science and clinical applications. Thanks to my incredible colleagues!

Great meeting with Dr. Yingming Zhao from UChicago after reading his work for years! His insightful talk was truly inspiring. Learned a lot and excited about potential collaborations in the future!

Happy to have my postdoc mentor, Phil, visit me after a few months here! Despite his incredibly busy schedule, he took the time to visit my lab space and meet with my trainees. I’m so grateful for his guidance as always. Looking forward to our next meeting!

David Lombard gives an overview of active discussions related to #aging and #metabolism at the ⁦Sylvester Comprehensive Cancer Center⁩ annual retreat ⁦Miller Medicine⁩

My first time at the 6th Miami Epigenetics and Cancer Symposium! Incredible to hear top experts share advances in cancer epigenetics, reconnect with old professors from Boston, meet new friends, and honored to serve as a discussion chair for the first time!

Looking for a #postdoctoral fellowship in mass spectrometry imaging related to small molecules and metabolism? Please reach out! Projects entail method development, use of derivatization, use of models and human cancer tissues! The Postdoctoral Am Soc for Mass Spec nimasharifilab.com/careers

Our DSUI Thanksgiving celebration was wonderful! Grateful for amazing colleagues, delicious food, and a warm sense of community. Thankful to DSUI for giving me the opportunity to start my lab and to my incredible lab members for making science exciting and fulfilling every day!

Excited to share our new nucleosome assembly method for asymmetric PTMs by a cyclic sortase, combined with middle-down proteomics! This could help solve many long-lasting biochemistry puzzles. Thanks to all the authors for their incredible contributions! pubs.acs.org/doi/full/10.10…

Thanks to all the support, I started my new role at the UMiami DSUI/SCCC this year! As a new PI, I’ve been focused on establishing my lab, applying for grants, and passionately mentoring postdocs and undergraduate students in exciting research projects. Grateful for this journey!

Hiring! After six months in Miami, I’m excited to officially launch this new journey. Seeking motivated postdocs to join our lab at the UMiami Miller School of Medicine, exploring protein epigenetics and chemical proteomics in cancer and aging. zawanglab.com/publications

Great honor to give a talk at #DSUIOnTheBeach25! Amazing discussions and looking forward to future collaborations!

Full house for the Miami Symposium on Human Metabolism! Nima Sharifi kicking off an exciting day talking about science! Desai Sethi Urology Institute #MSHM

Today in nature we share our back-to-back stories with Ning Zheng revealing chemical-genetic convergence between a molecular glue & E3 ligase cancer mutations. 1/6

Hiring: Post-Doctoral Associate in Urology at the University of Miami—advance cancer and aging research using chemoproteomics, protein chemistry, and nucleosome biology. umiami.wd1.myworkdayjobs.com/UMCareerStaff/…

Excited to be part of this work just published in JACS! This study introduces a robust ultrasound-induced desulfurization (USID) method for protein synthesis, enabling clean, scalable, and functionally compatible desulfurization under mild conditions. pubs.acs.org/doi/full/10.10…

Honored to host Dr. Hong Liu from the Chinese Academy of Sciences, Shanghai Institute of Materia Medica! Her insightful talk shared valuable progress from natural product development through to clinical trials. Truly inspiring to see the bench-to-bedside journey!

How do #ketones impart their effects? Congrats Zhipeng A. Wang on his story elucidating a new mechanism just out in bioRxiv! In his exciting story he shows acetoacetate via #metabolism modifies mitochondrial cysteines! Desai Sethi Urology Institute Sylvester Comprehensive Cancer Center biorxiv.org/content/10.110…

Excited to share our latest study in JBC! We reveal how SIRT6 adapts to diverse histone acylations through structural and enzymatic plasticity, supported by a new cryo-EM structure of SIRT6 bound to H3K27-modified nucleosomes. jbc.org/article/S0021-…