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A beautiful bridging (pun intended) of basic science and technology!

Congratulations to the 2024 class of Regeneron #sciencetalentsearch finalists - inspirations and hopes for the future. Keep persevering, keep shining! Society for Science

Very cool - rejuvenation of the immune system! nature.com/articles/s4158…

Inspiring visit at the Arc Institute today with Patrick Hsu & Silvana Konermann. Thoughtful vision, exciting science, and amazing potential.

Congratulations to all of the graduates during this commencement season! Wishing you all a creative and fulfilling future!​​​​​​​​​​​​​​​​ "What you follow with your heart will indeed come back to make your life much richer."

Nature is amazing! Congratulations to Max Wilkinson and team on a beautiful study revealing a clever way that bacteria defend against viruses. Check out Max’s posts for more detail! doi.org/10.1126/scienc…

Excited to see our team’s work on Fanzor now published in Cell! Amazing effort by Peiyu Xu and the entire team in uncovering the structural diversity and DNA cutting mechanisms of Fanzor. Proud of everyone involved! Onward to more discoveries. 🚀

Today we report Evo, a generalist foundation model for biology, on the cover of Science Magazine. Trained on billions of DNA nucleotides, Evo was designed to capture two key aspects of biology: the multi-modality of the central dogma and the multi-scale nature of evolution.

Happy 2025=1^3+2^3+3^3+4^3+5^3+6^3+7^3+8^3+9^3 and many new discoveries!

Congratulations to Rumya Mirco J. Friedrich Daniel Strebinger Blake Lash Cyrus Biotechnology and colleagues on an exciting study combining AI and protein engineering to minimize the immunogenicity of Cas9 and Cas12a nucleases. These approaches have the potential to improve the safety and

RNA-guided systems span kingdoms, from bacterial immunity to eukaryotic gene regulation. How did they evolve? We traced the origins of CRISPR-Cas13 and identified its likely ancestor: an RNA-based toxin-antitoxin (TA) system. Here’s what we uncovered: cell.com/cell/fulltext/… 1/8

#CRISPR revolutionized medicine, but where did its RNA-guided mechanisms come from? Using #AI, we unearthed new Cas13s and found they evolved from toxin-antitoxins, revealing how nature created these amazing reprogrammable molecules. Discover the recipe: doi.org/10.1016/j.cell…