On the way to Cranfield. Very happy to attend the ISM3S symposium, can’t wait to meet everyone. Zhugen Yang Cranfield University

"We describe an orthogonal DNA replication system in E. coli based on the ... replisome of bacteriophage T7. high transformation efficiencies and seamless integration into standard molecular biology workflows." Wonderful work from Peter Schultz and co!

Don't miss out on the captivating talks on 20th AUG! Join us for an exciting session with Dr. Daniel Dunkelmann and Dr. Joanna Sadler! Registration: eventbrite.com/e/991148781687…

My favourite discovery ever has just come online. Can I please tell you about some seriously wacky molecular biology? The story starts with a reverse transcriptase that SOMEHOW defends bacteria from viruses. (👇 I recommend sound ON for the video 🎹) 1/

Directed evolution of an orthogonal transcription engine for programmable gene expression in eukaryotes biorxiv.org/cgi/content/sh… #biorxiv_synbio

Great choice 👏

Watch Starship's fifth flight test x.com/i/broadcasts/1…

C/2023 A3 (Tsuchinshan–ATLAS) captured by my iPhone today #Comet

🎉 The highly anticipated iDEC Festival 2024 is happening on October 26-27 in Cambridge! 📍 Three distinguished scholars will deliver lectures at the awards ceremony. Stay tuned! ✨ #iDEC #directedevolution

📢 The iDEC Festival 2024 will take place at the beautiful Homerton College, University of Cambridge! 🌿14 teams will introduce their directed evolution projects—don’t miss it! 🔬Homerton Events #iDEC

I like two things about the iDEC: genuine inclusivity and, of course, strong enthusiasm for directed evolution. Thus, I am quite happy to give an opening talk at tomorrow's #iDEC2024 festival.

We are thrilled to announce the winners of iDEC 2024! 🏆🎉 Visit our website for the list of outstanding projects and teams that made it to the top: idec.io/pages/results2… #iDEC

Our work describing extensive gene divergence on laboratory timescales with upgraded OrthoRep systems is now out in Science Magazine here - science.org/doi/10.1126/sc…. X thread describing the preprint is quoted below. Congratulations to Gordon Rix and team!

Excited to report that we have discovered a new, endogenous molecular clock in unmodified human cells and tissues. It is ticking away right now in almost every cell in your body. Specifically, in a new paper on BioRxiv, we show that RNA editing by the near-ubiquitous ADAR1 in

A recent published SynBio paper's Supplementary PDF accidentally revealed the data storage folder on the author's computer—named '瞎编,' which translates to 'Fabricated.' - Unbelievable nature.com/articles/s4146…

Amazing: skin uses a commensal bacteria as a vaccine and loading new proteins on the commensals makes for new topical vaccines. Congratulations Michael Fischbach and team!

I've started visiting Phil Holliger lab at @MRC_LMB this week - its been inspiring and challenging in the best way! A short journey from JJ Thomson Avenue (electrons) to Francis Crick Avenue (nucleic acids) :)

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS, indeterminate dendritic cell histiocytosis

Today we report the directed evolution of HUH (a sequence-sequence covalent protein tag for ssDNA labeling) into rHUH, a sequence-specific covalent protein tag for RNA labeling. rHUH was hard to engineer: the initial HUH template had no RNA activity, so we started with RNA-DNA

We’re excited to share new work on the continuous in vivo evolution of gene libraries towards arbitrary functions. Led by superstar Olek Pisera, our experiments show that gene evolution is highly versatile...biorxiv.org/content/10.110…