Mitochondria- and ER-associated actin are required for mitochondrial fusion nature.com/articles/s4146…

Please join the Discovery Science Seminar Series in Chilcott at 12pm on Monday the 13th to hear from Min Wu, PhD. Geisel School of Medicine at Dartmouth Dartmouth 🌲 DartGRAD Dartmouth MCB Graduate Program Integrative Neuroscience at Dartmouth (IND) Dartmouth QBS BCBDartmouth Min WU Yale University

Paper now published in Current Biology! Current Biology Available here: authors.elsevier.com/a/1kPbA3QW8S6H…

What do action potential, hearing, calcium oscillations have in common? A periodic, synchronous opening of ion channels that we do understand. Our latest work proposes an alternative perspective for these conceptual problems beyond an ion flux-centric view. Feedbacks welcome!

And finally in print cell.com/current-biolog…

Fresh from the press with Nature Physics: How do we leverage a cell's self-organization to make it change its shape into a square? Check it out here: nature.com/articles/s4156… PhysicsOfLifeLMU Nikta Fakhri

I am happy to share our 5-year's work of manual mapping of all the native proteins in the golgin family, providing the highest resolution atlas of the Golgi apparatus to date! Yes, we can distinguish proteins at different cisternae.

Golgi apparatus is a daunting target for imaging for its uniquely stacked morphology throughout 3D space. To see how we combined super-resolution microscopy and biochemistry to study Golgi, please read our manuscript with all supplementary in BioRxiv: biorxiv.org/content/10.110…

4Pi-SMS and pan-ExM reveal, in a close collaboration with the Rothman lab, a surprising tetraplex organization and self-assembly of rim golgins, which we believe can explain stack formation of the Golgi apparatus: biorxiv.org/content/10.110…

A long-awaited mechanistic analysis of small GTPase biology and membrane pattern formation by the labs of Peter Bieling and Bill Bement Bement Lab embopress.org/doi/full/10.10…

Unlike eggs and mitotic cells, in adherent interphasic cells the centrosome is NOT positioned by a balance of forces along #microtubules, but by cell shape organization around the #centrosome. New from Schaeffer, Théry and colleagues: hubs.la/Q03hQjdn0

Actin waves + inverted LUTs 🤩 (bonus points if you can guess the cell type)

When Ca2+ oscillates, [Ca2+] is the variable. Is [Ca2+] also the control parameter that defines the system's stability? Happy to share our opinions: A molecular systems perspective on calcium oscillations beyond ion fluxes sciencedirect.com/science/articl…

Majority of data never get the opportunity to be published. This is F-actin clearly organized in two modes, clusters or meshes, possibly mediated by formins and Arp2/3.

I’m excited, relieved, and honored to announce that my paper describing non-canonical mitotic mechanisms in the early mouse embryo is out in Science Magazine ! (link at end of 🧵)

Realized this morning that my submission got selected Yale School of Medicine Beauty in Science 2025 exhibition! Seeing the live-assembly of filopodia projections by formin mDia3 in mast cells got me really stoked back then! #FluorescenceFriday

My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15

“Helsinki has not recorded a single traffic fatality in the past 12 months, city and police officials confirmed this week.” City engineer credits lower speed limits and smart design. I agree. #Helsinki #VisionZero yle.fi/a/74-20174831

Geng, Verhey et al find that KIF1C forms condensates where the exposed #kinesin motor domains entangle nearby #microtubules, causing them to bend & break in a process dependent on motor processivity, cluster properties, cytoplasmic viscosity, & MT anchors hubs.la/Q03C7Dbz0