Happy to announce that the Worden Lab is officially funded by @NIGMS! We also still have openings in the lab for ambitious postdocs! Apply 👇 (or email me) to join a vibrant and VERY supportive environment Van Andel Institute (VAI) in beautiful Michigan. jobs.silkroad.com/vai/VAICareerS…

Come join VAI for your postdoc! We are committed to giving our postdocs great support, starting with a salary floor of ~70k/yr! There are several open positions at VAI, and you can apply to my lab below. jobs.silkroad.com/vai/VAICareerS…

Always nice when you get some unexpected swag from your work! Van Andel Institute (VAI)

So glad to represent Van Andel Institute (VAI) at @sacnas. I had a great time hearing from so many promising scientists. See you next year!

Today I learned (again) that you could be breaking US laws for: - Mentoring a graduate student - Hosting a visiting scholar - Sending research materials to a colleague - Traveling to a foreign country Wonderful...

Happy holidays from the Worden Lab!

We are living in the golden age of structural biology.

Chromatin was a liquid crystal the whole time - got it. nature.com/articles/s4146…

I would like to share with you our new work on the identification of the first bona fide 'reader' of #histone H3K79 methylation, which has been a mystery since the discovery of this modification in 2002. science.org/doi/10.1126/sc… today online in Science Magazine

Human mRNAs form globules in 3D and are prepared for export by the transcription-export complex. We are excited to share this and more mechanistic insights in our newest work, co-lead by the fantastic Belén Pacheco-Fiallos and Matthias Vorländer. rdcu.be/c9e0f (1/9)

The Van Andel Institute (VAI) has an open faculty position in Structural Biology. Come join our vibrant research institute in Grand Rapids, MI and enjoy fantastic colleagues and support! Our search is open rank so please share with everyone, new or established! tinyurl.com/5a5uzh6u

Worden lab is excited for the Penn State Chomatin conference!

Congratulations to Dr. @BurtonNick, who earned a $2.9 million New Innovator Award from NIH Common Fund to find new ways to fix or prevent insulin resistance, a key driver of Type 2 #diabetes. #NIHHighRisk vai.org/new-innovator-…

Pleased to present our first preprint on how de novo DNA methylation occurs in di-nucleosomes. Lots of surprising findings about the linker length dependence of DNMT3 binding and activity. A great collaboration with the Peter Jones lab Van Andel Institute (VAI). tinyurl.com/47pmv7hy

Happy to share great work my postdoc Hemendra Panwar. By complete serendipity, he determined several structures of the native metazoan H/ACA snoRNP, explaining how contacts within the snoRNP regulate Pseudo-U deposition. Great collaboration with Dr. Ute Kothe. tinyurl.com/hrw2y9j4

Congratulations to VAI's Dr. H. Josh Jang, who has been appointed to assistant professor in our Department of Cell Biology. vai.org/article/van-an…

Today in the journal Science: BioEmu from Microsoft Research AI for Science. This generative deep learning method emulates protein equilibrium ensembles – key for understanding protein function at scale. msft.it/6010S7T8n

So many bittersweet emotions as I bid farewell to my first graduate student Dr. Leena Kariapper. Congratulations on completing your PhD and best of luck! We will miss you!