The cranial neural crest migrates into the multi-omics era: exciting review by our Vanessa Chong-Morrison and Tatjana Sauka-Spengler highlighting novel approaches to study NC gene regulatory dynamics - and the critical questions they might answer, now out Frontiers - Physiology shorturl.at/bBW57 🐟🐣

So pleased we published Pycro-Manager, a match made in heaven between Python and µManager. A big step forward for open-source microscopy control software!!

#ICYMI eLife - the journal A simple, cheap, and flexible PCR method to assay CRISPR sgRNA efficiency...try Headloop PCR! (1/4) 🧵

Jobs @Vastenhouwlab in beautiful CH: studying transcription factor clustering, gene movement, and all things related, in a developing embryo! Funded by European Research Council (ERC). Interested? Write me! Please RT. #transcription #chromatin #zebrafish #phaseseparation #postdocposition @cig_unil

Super excited to share our new preprint: A unified framework for quantitative protein and RNA imaging at high resolution with 1-step, isothermal, enzyme-free HCR signal amplification performed for all target proteins and RNAs *simultaneously*. #HCRimaging biorxiv.org/content/10.110…

It's official - a new era for Sauka-Spengler Lab! 🔥

New guidelines!: "When submitting a molecular biology manuscript, and when the paper is finally accepted, the authors must measure their epigenetic clock so that the reviewers can estimate by how much their lifespan has been shortened and whether they already suffered enough"

🧵A thread on cycling and Oxford🚴 A day before Ling Felce’s death on The Plain, I watched a former Witney mayor who killed a bike-keen grandfather on the roads walk from court. 1/

OH AGAIN SINGLE CELL RNASEQ "DISCOVER" EMBRYONIC CELL PROGENITOR BECOME EMBRYONIC CELL! MESODERM MAKE MESODERMAL DERIVATIVES! KNOWN TF ARE "PREDICTED"! EPIGENETIC HULK SO SO TIRED OF THIS! nature.com/articles/s4158…

#AskZebrafish Zebrafish Rock! Anyone in the UK in possession of codon-optimised mScarlet-I and willing to post an aliquot? Thank you 🙏

#preprint How do bilaterally equivalent structures in the forebrain become left-right asymmetric? A tale of zebrafish mutants, genetics, biochemistry, structural biology and Wnts. 🧵[1/13] tinyurl.com/3n76xpfu

Thank you to everyone for joining us at our Workshop on 'The Biology and Physics of Left-Right Patterning', organised by Gonca Erdemci-Tandogan Gonca Erdemci-Tandogan & Daniel Grimes Daniel T Grimes biologists.com/workshops/june… #BiologistsWorkshops

The comprehensive atlas of developmental regulatory elements in zebrafish is published today in Nature Genetics nature.com/articles/s4158…. In addition to the BioRxiv submission x.com/daniocode/stat… in this paper we added further resources and results. (1/n)

A few years ago, we Sauka-Spengler Lab wondered if Ac/Ds transposition could be harnessed to perform transient, F0 experiments in #zebrafish. We ended up with a toolkit to express enhancers, and sgRNAs for CRISPR...pleased that this story has now found a home with Biology Open #OpenAccess

Just a reminder that I am looking for 2 Postdocs to join my new group next year! There are no deadlines, but I have some great candidates so if you are thinking to apply then get in there soon!

If you're interested, our Zebrafish Plasmid Collection is a great place to start! addgene.org/collections/ze…

**We are moving platforms** Bioconductor will cease posting on Twitter/X as of December 17, 2023. Instead we will be continuing to post on other social media platforms that better reflect our community’s code of conduct. Read more in our blog post: buff.ly/3RddEAV

Exciting opportunity #ZebrafishJobs

Gaia Gestri, Anya Suppermpool @suppAnya and Kate Turner wrote a great piece on the UCL fish groups efforts in making our research a little bit more sustainable: Earning your Green stripes: enhancing sustainability in zebrafish research thenode.biologists.com/earning-your-g… via the Node

Happy International Women's Day 🫶 Today 100 women from across the MRC WIMM came together to mark the day and celebrate all the wonderful women who work and study at the institute 💜👩‍🔬👩‍🍳👩‍💻👩‍💼💜 #IWD2024 #InternationalWomensDay