Take a look at of programme for #TissueImmunology2023 on Friday 7th July! 🧾 We're very excited about wide variety of tissue-specific immunology on offer from our all of our speakers! 🧠🫀🫁 Here's a thread going through all the speakers we have in store 🧵

Session 3 - "Multi-tissue immunology" Starting with the wonderful Taams Lab, followed by selected talks from Umesh Dhawan, Régis Joulia and Laura Pallett And bringing our conference to a close we have our keynote speaker, Donna Farber! 🙌

Thank you very much, Mani Subramanian 🫀 It was truly an incredible experience to present our NET clearance story, and I am immensely grateful for your exceptional mentorship and invaluable guidance.

Great opportunity to do Ph.D. in a wonderful lab.

I’m incredibly excited to share our article, listed as co-first authors with wonderful Purbasha Bhattacharya Grateful for the support and guidance provided by exceptional supervisor Mani Subramanian 🫀

Led by Purbasha Bhattacharya and Umesh Dhawan, PhD, researchers at William Harvey Research Institute & CSIR-IGIB established a critical role for efferocyte-derived vesicular mediators in increasing #macrophage #efferocytosis efficiency. Take a look at their study in Cell Reports: 📘 bit.ly/43AR5cb

I am delighted to announce that I will soon join The Crick Institute in London! My lab will study how cancer affects the host "macroenvironment", especially the hematopoietic, cardiovascular, and immune systems. Sounds interesting? Join us! crick.ac.uk/research/labs/…

Excited to share the Way Lab Crick Waters new pre-print. ✨The beauty of combining brains, immunologists and cell biologists at play! Our work uncovers mechanistic insight for immunodeficiency developed under ARPC5 loss of function. biorxiv.org/content/10.110…

It's challenging for Indian research scholars today as they often do not receive regular fellowships, which affects their ability to focus on research. Many scholars experience significant stress in their daily research activities due to this uncertainty DSTIndia Abhay Karandikar

Job Alert! The Aramburu Lab MIMS - Molecular Infection Medicine Sweden Nordic EMBL P'ship is looking for a postdoc. If you are interested in discovering new #microproteins in innate immune cells and have a background in computational or proteomics, Apply or contact me. umu.varbi.com/what:job/jobID…

#QMPAW24 #LovePostdocs Millie Davan Wetton, William Harvey Research Institute

Impaired Macrophage DNase Secretion Promotes Neutrophil Extracellular Trap Mediated Defective Efferocytosis in Atherosclerosis biorxiv.org/content/10.110… #biorxiv_pathol

I'm very happy to share the work wonderfully done in Mani Subramanian 🫀 lab. Here, Umesh Dhawan, PhD and we show the importance of macrophages to clear NETs in the atherosclerosis context. It is really nice to collaborate with talented researcher in this relevant field. biorxiv.org/content/10.110…

Macrophage-derived DNases clear localized NETs, and impairment in clearance leads to persistent NETs and pathologies like atherosclerosis. Umesh Dhawan, PhD Mani Subramanian 🫀 biorxiv.org/content/10.110…

Excited to share our preprint! We show MΦ- DNases clear NETs in atherosclerotic plaques and foamy MΦs impair this, leading to defective efferocytosis → worsening plaque progression. #Efferocytosis #atherosclerosis Mani Subramanian 🫀 William Harvey Research Institute Luiz Vasconcellos biorxiv.org/content/10.110…

Want to know how NETs accumulate in atherosclerosis and exacerbate pathology? Read this phenomenal work by Umesh Dhawan, PhD and collaborators Luiz Vasconcellos Karran Bhagat aarushi Singhal University College Dublin UKE Hamburg CSIR-IGIB British Heart Foundation Barts Charity William Harvey Research Institute doi.org/10.1101/2025.0…

Delighted to share my first author original publication in the journal of Diabetes, from the output of my PhD work, highlighting the importance of investigating sex differences in diabetic cardiomyopathy! William Harvey Research Institute Barts and The London, Queen Mary American Diabetes Association diabetesjournals.org/diabetes/artic…

Happy to share this work that gave me hard time through the last years! #antigenpresentation #pi3k #IBD #immunesignalling biorxiv.org/content/10.110…

I’m happy to share our latest work on tumour necrosis! During my time in the Mikala Egeblad lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13) nature.com/articles/s4158…

Proud to share Jose M. Adrover’s (new PI The Francis Crick Institute) paper: As a postdoc (Cold Spring Harbor Laboratory/Johns Hopkins Medicine), he found #NETs in necrotic tumors—I shrugged. But he looked closer: NETs block tumor vessel perfusion, causing necrosis, hypoxia, EMT & #Metastasis. nature.com/articles/s4158… @JHU_BDP nature