Just returning from fantastic Sepsis Update Meeting in Weimar. Thanks for three wonderful days Frank M. Brunkhorst

Bayesian analysis #HOTICU, large mortality-effects unlikely, potential higher mortality with low O2-target and high norepinephrine doses British Journal of Anaesthesia Thomas Lass Klitgaard Anders Granholm ICU Management ESICM bit.ly/2Z2bagq

In an open letter to Mark Zuckerberg, editors at The BMJ Fiona Godlee and Kamran Abbasi urge Facebook to correct a “fact check” of a recent investigation that they say is “inaccurate, incompetent, and irresponsible” bmj.com/content/375/bm…

Potential benefit of higher oxygenation strategy in patients with shock #HOTICU British Journal of Anaesthesia bjanaesthesia.org/article/S0007-…

The one year outcomes of the HOT-ICU trial will be presented at #CCR22 by @BodilSRasmussen What effect will lower or higher oxygenation targets have on longer term functional outcomes like cognition? Join us in June to find out! criticalcarereviews.com/meetings/ccr22

World Delirium Day 16/3 2022 Focus On delirium. #AIDICU TRIAL soon finish recruitment!@CRIC_Int_Care Lone Musaeus Poulsen Nina A-Ranberg Ole Mathiesen @AndersPerner Camilla Bekker and a new association In Denmark #danishdeliriumassociation

Lower (8 kPa) vs higher oxygenation (12 kPa) targets: no longterm survival benefit nor HRQoL improvement at 1y in #ICU pts with severe hypoxaemia (HOT-ICU trial cohort). Substantial impairments in several EQ-5D-5L dimensions in survivors in both groups. 🖇️ bit.ly/3EwbfJm

Newest insights from the HOT-ICU trial