THYRAGE study
@thyragestudy
Investigating influence of #thyroid on #osteoporosis, #osteoarthritis, #neurodegeneration, #sarcopenia. Receives funding of #H2020 πͺπΊ
ID: 700800476988575744
http://www.thyrage.eu/ 19-02-2016 21:53:48
732 Tweet
362 Followers
455 Following
Different hormonal axes appear to have interplay over 24 hours in healthy older adults, with slightly different patterns for men and women Endocrine Society buff.ly/2Hx6vtF #endocrinology #physiology #THYRAGE
Last week Maxime Bos successfully defended her thesis on genetics and lifestyle in relation to cardiometabolic diseases. Congratulations doctor Bos! Find the link to her thesis here:buff.ly/3liyiwp #THYRAGE #PhD #celebration
How to detect measurement errors in 24-hour hormone data? This paper compares different methods and recommends a stepwise approach. Sage Health & Nursing buff.ly/3mLf0Bz #methodology #errordetection #THYRAGE
Precise regulation of thyroid hormone availability inside skin cancer skills regulates tumor progression Nature Communications buff.ly/3k7XqFq #THYRAGE #openaccess #thyroid #oncology #molecular
The cancer-related NANOG transcription factor induces expression of thyroid hormone activating enzyme deiodinase type 2 inside skin cancer cells Cancers MDPI buff.ly/368Ws6M #THYRAGE #openaccess #thyroid #oncology #molecular
Skin cells naturally deactivate thyroid hormone, without this capacity wound healing and hair growth is altered. American Thyroid Association buff.ly/3mTXlXx #THYRAGE #thyroid #physiology #molecular
Older adults are likely to be excluded from 100% of the COVID-19 vaccine trials!π JAMA Internal Medicine buff.ly/2JizTVJ Exclusion of older adults in clinical trials is generally common, impeding evidence-based medicine in older adults.#clinicaltrials #geriatrics #CovidVaccine
Frailty and pre-frailty are associated with future risk of dementia in UK Biobank. Does that make frailty an early marker of dementia or a modifiable risk factor?π€ The Lancet Healthy Longevity buff.ly/39qnBp6 #frailty #dementia #ukbiobank #geriatrics
Experiencing a delirium appears to independently increase long-term cognitive decline in both surgical and non-surgical patients. JAMA Neurology buff.ly/2Ji1BC1 #geriatrics #dementia
Targeted prevention was highly effective in Chinese surgery wards with a number needed to treat of only 6 to prevent 1 delirium. Question remains how to translate this study to other settings.JAMA Internal Medicine buff.ly/2HU4OHm #geriatrics #delirium #surgery #clinicaltrials
Time-restricted eating revealed no large benefits in weight loss or metabolic measures compared to a structured diet of three meals per day in overweight and obese individuals JAMA Internal Medicine buff.ly/35oA0ai #weightloss #IntermittentFasting #diets #metabolism #obesity
Mitochondria in specific areas of the brain are highly responsive to feeding and fasting, they play a crucial role in glucose homeostasis and in whole-body metabolism Frontiers - Endocrinology buff.ly/3no3sTO #metabolism #mitochondria #molecular #neuroendocrine #Review
Individual cells communicate with each other in various ways. This review summarizes mechanisms and methods to measure them. Nature Reviews Genetics buff.ly/3bkv3D2 #molecular #singlecellsequencing #Review #homeostasis
When confronted with enodplasmatic reticulum stress, thyroid cells dedifferentiate in order to survive. Consequently, there is mesenchymal shift with less active gland tissue. Frontiers - Endocrinology buff.ly/3hXHHsL #thyroid #cellstress #antioxidant #cellfate #molecular #aging
One of the factors contributing to age-related degenerative diseases might be a synergistic interaction of inflammation and oxidative stress Frontiers - Endocrinology buff.ly/38ryxS9 #molecular #aging #oxidativestress #inflammation #inflammaging