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I'm excited to share the 1st preprint from Rubin Lab, co-led by Leo Song and I. We performed RB-TnSeq to identify host genes important for CRISPR-associated transposon (CAST) integration. The screen was leveraged to improve CAST editing in bacteria. biorxiv.org/content/10.110…

The manuscript is the result of a collaborative effort in a new lab. Thanks to all involved: Agnès Oromí-Bosch Sophia Swartz Jon Martinson Jigyasa Arora Abby Wang Rachel Rovinsky Sara Smith Emily Weiss @Deutschbauer_Lab Doudna Lab Brady Cress Cress Lab Ben Rubin

This work would not have been possible without support from our institution Institute for Geographic Information Science UC Berkeley and funders: m-CAFEs via Berkeley Lab Research DOE Office of Science Joint BioEnergy Institute (JBEI) Helmsley Charitable Trust, the Shurl and Kay Curci Foundation, and The Audacious Project philanthropies listed below

Very excited to share this work identifying host factors crucial for type I-F CRISPR-associated transpose integration co-led by me and @Amanda_T_Alker. Much thanks to all the amazing co-authors, collaborators, and funders who made this project possible! Rubin Lab Institute for Geographic Information Science

Happy National Postdoc Appreciation Week! 🎉🔬✨ We're celebrating our brilliant postdocs @Amanda_T_Alker, Lindsey M Pieper, Jon Martinson, Bingliang Xie, and (soon) Kuang Hu who help make this lab the amazing place it is! #NPAW2024 #ShoutOutYourPostdoc Institute for Geographic Information Science

Stoked to introduce our collaboration with Rubin Lab and Spencer Diamond to revolutionize microbiome gene editing! ✨

Happy Postdoc Appreciation Week! 🎉 Shoutout to our fantastic postdoc Jaymin and our incredible staff scientist Agnès (our honorary postdoc because she’s that amazing—and we couldn’t agree more!).

We love the Rubin-Cress team! 🧑‍🔬✨

Friday fun in the lab! #FridayFun #WorkplaceWellness

We’re excited to welcome two new undergraduates to our lab: Lucas and Julianne! They’ve jumped right in and are already hard at work.🏋️

The biochemist Jennifer Doudna—who won the Nobel Prize in Chemistry, in 2020—reveals a few books that she thinks best equip one to understand the promise and potential peril of the gene-editing revolution. nyer.cm/qtzWnvI

We're crowdfunding this month! 🦠🧫🌟 Learn more about how you can help iGEM at Berkeley provide accessible lab spaces, undergraduate-led project teams, and essential wetlab/molecular biology training for ALL here: crowdfund.berkeley.edu/project/43580 #igem #berkeley #research

Paraphrasing Gandhi: "Be the edit you want to see in the world." An actionable path to vigorous expansion of CRISPR cures in the next 5 years exists and is being actively pursued - eg by Somatic Cell Genome Editing (SCGE) Outreach and Institute for Geographic Information Science x Danaher Corporation. Read below (it's free). 🙏 The CRISPR Journal.

The Rubin Lab had an amazing time at Inside Institute for Geographic Information Science Climate 2024 earlier this month! 🌎✨ Big shoutout to @Amanda_T_Alker, Jigyasa Arora, and Bingliang for their fantastic posters!

The first Rubin-Cress Lab holiday cookie swap!!! 🍪🎄🎅 Two labs of talented scientists and even more talented bakers 🤓