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#TB friends!! Deadlines are approaching for Keystone Symposia #Tuberculosis : Heterogeneity from Models to Human Disease, this February in Boston! See scholarship, abstract and discount reg dates: keysym.us/KSTB25 #KSTB25

Has anyone had success with targeting proteins to the lysosome using something other than LAMP sequences?

Anyone know where I can order milligram quantities of human MHC-II (with or without peptide?) NIH tetramer core is great but only does hundreds of micrograms.

This approach has been truly indispensable for us. Rigorous biochemical validation of immunopeptidomics data is super important!

TB friends! Anyone have a human CD4+ T cell clone that recognizes PPE18/Rv1196?

There is still about a month to apply to our faculty position in #immunology and #immunoengineering MIT Dept of BE! We look forward to reading your applications be.mit.edu/about/open-fac…

Anyone else see this paper? Perhaps a genome architecture explanation for NOS2 in mice v humans. cell.com/cell-reports/f…

Does anyone have favorite cell membrane/cytoplasm dyes for multi-day live cell imaging that are ideally 405-excitable and don’t induce appreciable phototoxicity?

Immunopeptidomics (impep) friends, have you ever done impep to ID peptides after soluble protein delivery to phagocytes to look at peptides generated by XP?

AbMAP, our work on adapting PLMs for antibodies, is now out in PNASNews. A veritable zoo of PLMs now exists, so why should you care? Well, AbMAP reflects an opinionated design philosophy about antibody representation. If that design fits your need, it may be great for you! 1/

Does anyone have an in vitro T cell priming protocol they have successfully used in human PBMCs?