💉 In a small RCT of IL-7 for refractory MAC lung disease, IL-7 increased lymphocyte counts but failed to convert sputum cultures. Structural lung disease may trump immune dysfunction in driving outcomes. journals.sagepub.com/doi/full/10.11…

🚨 Submission Open! 🚨 🦠 Antimicrobial Resistance Mechanisms & Therapeutic Options for Difficult-to-treat Nosocomial Pathogens 🌍 📅 Deadline: Dec 31, 2025 📚 Submissions are now welcome! For full details, check out the link. journals.sagepub.com/topic/collecti…

As SOT/HCT recipients and cellular therapy patients travel more, tailored pretravel evaluations are critical: risk stratification, vaccines, prophylaxis, and counseling. journals.sagepub.com/doi/full/10.11…

Whole Body FDG-PET/CT (WBP) in Endocarditis 📊 Management changed in 44.6% of cases—esp. in prosthetic/device-related IE 💊 Led to longer + suppressive abx ⚠️ No difference in mortality or LOS 👀 Highlights need for clearer guidance on WBP use in IE journals.sagepub.com/doi/full/10.11…

High resistance to amoxicillin (>95%) in UTI pathogens in Nepal. E. coli & K. pneumoniae still largely susceptible to gentamicin; E. coli to nitrofurantoin too. Regional data critical for guiding empiric therapy. journals.sagepub.com/doi/full/10.11…

📍SFTS: Hemorrhagic fever by Bandavirus dabieense ✅ Favipiravir > Ribavirin ❌ Platelet transfusions don’t help ⚠️ IVIG, IFN, steroids may worsen outcomes 🧬 Tocilizumab, ruxolitinib, plasma exchange show promise 🚀 Future: FDA drug screens + multiomics journals.sagepub.com/doi/full/10.11…

This vivid case of colonic hookworm bleeding in an HIV+ patient highlights the hidden toll of neglected tropical diseases—underdiagnosed, undertreated, yet responsible for enormous morbidity in low-resource settings. journals.sagepub.com/doi/full/10.11…

By 2050, antimicrobial resistance (AMR) may cause 10 million deaths annually. Not just superbugs—resistance is rising in fungi, viruses, and parasites. This review highlights the escalating threat of AMR journals.sagepub.com/doi/full/10.11…

Is there a “weekend effect” in ICU care for infected patients? 🇯🇵 Analysis from Japanese ICUs (DIANA cohort) finds no significant difference in ICU discharge or mortality at 14/28 days between weekend vs weekday admissions. journals.sagepub.com/doi/full/10.11…

🚨 Rising drug-resistant #TB in Tanzania threatens SDG3 progress. Using Bayesian zero-inflated Poisson models, this study maps high-risk areas & identifies key drivers: sex, age, HIV status & prior TB treatment. journals.sagepub.com/doi/full/10.11…

🚨 Study from Malawi: Among people with HIV admitted to hospital, inability to walk unaided predicted in-hospital death as well as the full WHO or qSOFA scores (AUROC ~0.68–0.71). journals.sagepub.com/doi/full/10.11…

Among adults with HIV in Zambia, kidney impairment (eGFR <60) affected 10.7%. Risk was significantly higher in older adults and those on DTG + TDF/3TC regimens. 🩺 Monitoring renal function in PLWH on ART is critical. journals.sagepub.com/doi/full/10.11…

🧫 In a microbiome sub-study of patients on antibiotics: 💊 Ampicillin, piperacillin-tazobactam,&meropenem → • ↑ Enterococcus faecium colonization • ↑ ARGs (blaTEM-1A, blaSHV-100, blaCMY-18) • ↓ beneficial anaerobes (Clostridium, Bifidobacterium) journals.sagepub.com/doi/full/10.11…

📚Submissions open for the collection -Case Reports from the Global South: Learning from Low- to Mid-Resource Settings 🗓️ Deadline: November 28, 2025 💡 Showcase innovation,resilience, & local expertise in resource-limited settings. Andrés Henao, MD, PhD journals.sagepub.com/topic/collecti…

COVID-19 unmasked plastic bronchitis in a man with HIV & Kaposi sarcoma. Not all dyspnea in PWH is infection—think rare complications. journals.sagepub.com/doi/full/10.11…

TB care ≠ just antibiotics. In Ghana, many patients had persistently poor QOL after 6 months. Mental health, stigma, & social support must be addressed. journals.sagepub.com/doi/full/10.11…

🚨 Submission Open! 🚨 🦠 Antimicrobial Resistance Mechanisms & Therapeutic Options for Difficult-to-treat Nosocomial Pathogens 🌍 📅 Deadline: Dec 31, 2025 📚 Submissions are now welcome! For full details, check out the link. journals.sagepub.com/topic/collecti…

From barrier to trigger: skin microbiota guard us but can also drive disease when balance falters. Latest review explores mechanisms and emerging microbiome therapies. journals.sagepub.com/doi/full/10.11…

📌 New study finds 33% of Hep B treatment-naïve patients already harbor primary antiviral resistance mutations—mostly rtV207M. ⚠️ No clear link to genotype or clinical factors 👉 Genotypic screening crucial to guide therapy and prevent treatment failure. journals.sagepub.com/doi/full/10.11…

Staph aureus bacteremia still deadly. β-lactam combos: faster clearance, variable survival benefit, AKI risk. journals.sagepub.com/doi/full/10.11…