We are thrilled to share this work linking specific human brain cell types to psychiatric and neurological disorders, out now in Nature Neuroscience rdcu.be/d6Tcy See below for an overview and thanks to the amazing Tayden Li, William Giardino, Deis Sero, and so many others!

How do we detect spatially variable genes (SVGs) in spatial transcriptomics? In our Nature Communications review, we categorize 34 computational methods into three categories: ✅ Overall SVGs ✅ Cell-type-specific SVGs ✅ Spatial-domain-marker SVGs link.springer.com/article/10.103… 1/1

Excited to share our new method, TWiST, for transcriptome-wide association studies (TWAS) using single-cell eQTL data. TWiST advances beyond pseudobulk aggregation and captures heterogeneous gene-disease associations within cell types. Check out our preprint below 👇

We’re excited to announce two nature publications from Project AMIE (Articulate Medical Intelligence Explorer), a research AI system optimized for diagnostic reasoning and conversations 💬 Paper 1: goo.gle/4lpQ8xg Paper 2: goo.gle/3G4DNPe

Today in nature, we report a spatial single-cell atlas of human cortical development, revealing surprisingly early specification of human cortical layers and areas. We built an interactive browser to explore the spatial data: walshlab.org/research/corte… Paper link below👇

Yale and Google trained a 27B parameter model, C2S-Scale, to unify single-cell transcriptomics and biological language for deep reasoning across genes and cells. It outperforms prior models in interpretation, QA, and perturbation prediction using reinforcement learning

Today we are releasing ether0, our first scientific reasoning model. We trained Mistral 24B with RL on several molecular design tasks in chemistry. Remarkably, we found that LLMs can learn some scientific tasks more much data-efficiently than specialized models trained from

This is effectively a cure for type 1 diabetes. Autologous, (chemically) reprogrammed iPSCs were engineered from a patient's fat cells and injected back into her stomach. After ~2.5 months, she no longer needed insulin and now enjoys ice cream + candy like a normal person.

To the 23andMe Community, I am incredibly excited and humbled to share with you that TTAM Research Institute (TTAM), a new non—profit medical research organization that I founded and lead, has completed the acquisition of 23andMe.   I formed TTAM and pursued the acquisition of

Happy to share that our work from the Nicholas Mancuso lab is out in Nature Genetics! We developed SuShiE, a multiancestry fine-mapping method for molecular traits. doi.org/10.1038/s41588…