Glad to share our latest work in The FEBS Journal. Our successful characterization of prokaryotic Ras-like GTPase SofG. Shows that MglB acts as a GAP for both SofG and MglA. This is the first demonstration of a dual-specificity GAP in prokaryotes. IISER Pune febs.onlinelibrary.wiley.com/doi/10.1111/fe…

Looking forward to reading about 2x function GAPs discovered by Gayathri's team. Nice to see this work is out #microbial #cellbio #signalling #GTPases febs.onlinelibrary.wiley.com/doi/10.1111/fe…

Our discovery of first prokaryotic dual GAP.

Very happy to share our new work by Jonas Tholen on the mechanism of branch site recognition by the human spliceosome. science.org/doi/10.1126/sc… EMBL @emblgrenoble European Research Council (ERC) #cryoEM #splicing #RNA #ERCStG

EMBL highlighted our recent article in Science Magazine Check out the link for an explanation of why our work matters ⬇️

EMBL highlights our recent paper on the U2 snRNP structure and branch site recognition in human cells. Work by a PhD student in the lab Jonas Tholen #cryoEM #splicing #RNA #ERCStG

EMBL embarks on a new era of molecular biology. EMBL research will expand to study life in context – from molecules to ecosystems. Broad in scope, our next programme encompasses fundamental research, services & multidisciplinary collaboration. embl.org/news/lab-matte…

And the moment has arrived... The 24th annual EMBL PhD symposium is open for registration! Don't miss the opportunity to register! Information on the scientific program is available on our website (phdsymposium.embl.org)

Interested in the mechanism of pre-mRNA splicing? Check out our latest review by @structjon in Current Opinion/Research in Structural Biology authors.elsevier.com/sd/article/S09…

Congratulations Jonas Tholen. 🎉

Great news! Congratulations to all the winners, including our own Jonas Tholen from EMBL Grenoble EMBL

EMBL Grenoble's amazing surroundings are among the very greatest things about working here!🏔️ Last week we enjoyed our traditional LabSkiDay! 🎿❄️

Looking for a PhD? Come and join us at EMBL Grenoble. We have some exciting projects in structural biology of complexes regulating pre-mRNA splicing and gene expression

Happy to share our new work on the U11 snRNP, the key building block of the human minor spliceosome complex. biorxiv.org/content/10.110… #cryoem #spliceosome #RNP #splicing #mRNA European Research Council (ERC) EMBL

Meet Jiangfeng Zhao from China, postdoctoral fellow at EMBL Grenoble. His research focuses on the spliceosome, an essential and complex molecular machine that selects and removes the non-coding RNA (introns) that are unnecessary for producing mRNAs and functional proteins.

U5 snRNP is one of the key building blocks of the spliceosome, but how it is assembled and recycled remains unknown. Check out our latest paper to find out more about this process: nature.com/articles/s4159… #RNP #splicing #cryoEM EMBL Grenoble European Research Council (ERC)

Another year, another LabSki Day! ❄️ Last week, we enjoyed EMBL Grenoble's amazing surroundings - a tradition since 1991! 🏔️

EMBL researchers have provided new structural insight into the splicesome – a molecular machine involved in the maturation of mRNA molecules. A deeper understanding of the spliceosome could pave the way for novel therapies for genetic disorders. embl.org/news/science-t…