Just published in The Lancet! ‼️🗞️ ESGO-ESTRO-ESP Guidelines for the Management of Patients with Endometrial Carcinoma: 2025 Update These guidelines are an update from the prior guidelines published in 2021 and cover all relevant aspects of diagnosis, management, follow-up &

#Osteoporosis is a common condition among older adults that leads to increased susceptibility to fracture. ➡️ Learn more about the epidemiology, diagnosis, and treatment of osteoporosis in this review. ja.ma/4m0B7SL

Episiotomy to prevent obstetric anal sphincter injuries during instrumental delivery in nulliparous women: a national prospective comparative cohort study ow.ly/cZG750WyvmE

𝗠𝗲𝗰𝗵𝗮𝗻𝗶𝘀𝗺𝘀 𝗼𝗳 𝗔𝗰𝘁𝗶𝗼𝗻 𝗼𝗳 𝗧𝗲𝘀𝘁𝗼𝘀𝘁𝗲𝗿𝗼𝗻𝗲 Many of the benefits and some of the risks of testosterone treatment are mediated by the mechanisms through which testosterone acts. Testosterone has anabolic effects on muscle (panel A) and bone (panel B) and

An update to the Obesity Canada Pharmacotherapy Clinical Practice Guidelines, published today. An emphasis on each medication's potential to impact individual obesity-related complications ttps://www.cmaj.ca/content/197/27/E797

🚨BREAKING: FDA grants accelerated approval to Wegovy (semaglutide 2.4 mg injection) for treating adults with non‑cirrhotic metabolic dysfunction‑associated steatohepatitis (MASH) with moderate to advanced liver fibrosis - - - A Fourth Indication for Wegovy Wegovy’s FDA-approved

A recent study showed that newborns have high levels of p-tau, a biomarker for #Alzheimer disease. Understanding how infants clear the protein could help prevent aggregation, which leads to #neurodegeneration in adults. ja.ma/4mdpjfX

New brain-targeting anti-obesity peptides (GLP-1, GIP, and dual agonists) access brain sites, such as the area postrema and arcuate nucleus, where they engage neurons controlling appetite, energy use, and reward response. By tapping into these circuits, they help suppress hunger

Elinzanetant for Vasomotor Symptoms from Endocrine Therapy for Breast Cancer (OASIS-4) nejm.org/doi/full/10.10…

Treatment of uncomplicated vulvovaginal candidiasis: topical or oral drugs? Single-day or multiple-day therapy? A network meta-analysis of randomized trials - Network characteristics of early clinical cure ow.ly/ZMLc50WKMc2

The latest EMAS Clinical Guide on Endometriosis and Menopausal Health is now available. This guide provides evidence-based recommendations for healthcare professionals worldwide. #Endometriosis #Menopause European Menopause and Andropause Society (EMAS) 👉 Read the full article pubmed.ncbi.nlm.nih.gov/40907339/

Misconceptions keep some cancer patient populations from benefitting from hormone therapy, more education is needed. Read more at tinyurl.com/2yp5wz24. #hormonetherapy #gynecologiccancer

🚨 Un fármaco para el tratamiento de la pérdida de peso y la diabetes también frena el envejecimiento 🧬 Semaglutida en 32 semanas: 📉 –3 a –5 años en relojes biológicos ⏱️ ~9% más lento el ritmo de envejecimiento ⏳ Cuidar la salud metabólica es también medicina de longevidad.

The new #LancetCommission obesity definitions show dramatic differences in risk: 🏈 Athlete, BMI 32—WHO called it class I obesity; now “no obesity” 👵 Older woman, BMI 27+diabetes—WHO overweight; now stage 2 clinical obesity 👩 Woman, BMI 33+prediabetes—WHO class I; now stage 1

Phase 3 trial just published in NEJM for #orforglipron, an oral GLP-1 medication for obesity. At the highest dose, participants saw an average 11.2% weight loss, with 36% losing at least 15% and 18% losing at least 20% of their body weight. Cardiometabolic markers also improved.

Guías de evaluación y tratamiento de la obesidad 2025 por la AACE. Para todos los profesionales de la salud 👇 Referencia: doi.org/10.1016/j.epra…

Excelente imagen de los diferentes fármacos GLP-1 aprobados y los que vienen en camino. Mecanismos de acción, muy gráfico !!📊 Para las diapositivas 👏🏻👏🏻👏🏻 👇🏻👇🏻👇🏻👇🏻 JAMA

Both combined and progestin-only contraceptives are linked to increased breast cancer risk, with greater risk observed for progestin-only, particularly desogestrel-containing products. ja.ma/47vFzD3

While the use of fertility-preserving #HormonalTherapy for early-stage endometrial #cancer has increased, survival outcomes are comparable to #hysterectomy in patients under 40. ja.ma/3LdSq5i

Today, World Health Organization (WHO) published a guideline in JAMA on the use and indications of #GLP1 therapies, including GLP-1 receptor agonists and GLP-1/GIP dual agonists, for the global treatment of #obesity in adults. ja.ma/48CbXFB 🧵