Wiep Klaas Smits (@smitslab) 's Twitter Profile
Wiep Klaas Smits

@smitslab

Assoc. prof. @LUMC_Leiden/CMAT. Cdiff, DNA replication, AMR, microbiome, anaerobes. Clostpath SC. Education officer ESGCD. Also: @smitslab.bsky.social

ID: 3414880439

linkhttp://www.lumc.nl/smits calendar_today11-08-2015 10:23:52

13,13K Tweet

2,2K Followers

2,2K Following

Wiep Klaas Smits (@smitslab) 's Twitter Profile Photo

Host origin of microbiota drives functional recovery and Clostridioides difficile clearance in mice | mBio journals.asm.org/doi/10.1128/mb…

Nature Microbiology (@naturemicrobiol) 's Twitter Profile Photo

Out Now! Peptidoglycan–outer membrane attachment generates periplasmic pressure to prevent lysis in Gram-negative bacteria bit.ly/4kZA3gF #Peptidoglycan #BacteriaResearch #Microbiology

Out Now! Peptidoglycan–outer membrane attachment generates periplasmic pressure to prevent lysis in Gram-negative bacteria bit.ly/4kZA3gF #Peptidoglycan #BacteriaResearch #Microbiology
Niko McCarty 🧫 (@nikomccarty) 's Twitter Profile Photo

This paper is really elegant and beautiful. Researchers took a vesicle, filled it with a single type of enzyme and some protein pores, and showed that this "minimal cell," made from just three components (!!), could "actively propel itself toward an enzyme substrate gradient."

This paper is really elegant and beautiful.

Researchers took a vesicle, filled it with a single type of enzyme and some protein pores, and showed that this "minimal cell," made from just three components (!!), could "actively propel itself toward an enzyme substrate gradient."
Staph papers (@staph_papers) 's Twitter Profile Photo

The impact of rifampin on the efficacy of implant retention and prosthesis removal in staphylococcal periprosthetic joint infection ift.tt/JQIGV0h

Wiep Klaas Smits (@smitslab) 's Twitter Profile Photo

DNA replication initiation timing is important for maintaining genome integrity | Journal of Bacteriology journals.asm.org/doi/10.1128/jb…

Wiep Klaas Smits (@smitslab) 's Twitter Profile Photo

Paper alert! 🚨 Draft and complete genome sequences of 17 Streptococcus species | Microbiology Resource Announcements journals.asm.org/doi/10.1128/mr…

Wiep Klaas Smits (@smitslab) 's Twitter Profile Photo

Paper alert! 🚨The 1st manuscript resulting from a collaboration with Polish colleagues: frontiersin.org/journals/micro… We confirm in this manuscript that Polish and UK outbreak isolates of RT955 are genomically related and show that RT027 remains dominant in Poland.

IBFG (@ibfg_es) 's Twitter Profile Photo

New paper published in Nature Microbiology! 🆕 📃 🥼 Led by Narciso Martín from IBFG in collaboration with the University of Salamanca and Université Laval ⚙️ This study introduces FungAMR and ChroQueTas — two groundbreaking tools to tackle antifungal resistance 🧶⬇️

New paper published in Nature Microbiology! 🆕 📃

🥼 Led by Narciso Martín from IBFG in collaboration with the University of Salamanca and Université Laval

⚙️ This study introduces FungAMR and ChroQueTas — two groundbreaking tools to tackle antifungal resistance

🧶⬇️
Wiep Klaas Smits (@smitslab) 's Twitter Profile Photo

Kabli, A.F., Ng, I.W., Read, N. et al. Coupling chromosome organization to genome segregation in Archaea. Nat Commun 16, 6759 (2025). doi.org/10.1038/s41467…

Wiep Klaas Smits (@smitslab) 's Twitter Profile Photo

Clostridioides difficile toxins alter host metabolic pathway and bile acid homeostasis gene expression in colonic epithelium | Infection and Immunity journals.asm.org/doi/10.1128/ia…

Wiep Klaas Smits (@smitslab) 's Twitter Profile Photo

Inhibition of Clostridioides difficile-specific DNA adenine methyltransferase CamA by analogs of S-adenosyl-L-methionine biorxiv.org/content/10.110…

Wiep Klaas Smits (@smitslab) 's Twitter Profile Photo

Molecular basis of Fab-dependent IgA antibody recognition by gut-bacterial metallopeptidases | The EMBO Journal embopress.org/doi/full/10.10…

Wiep Klaas Smits (@smitslab) 's Twitter Profile Photo

An endoribonuclease of the YicC-like family delays sporulation via sRNA degradation in Clostridioides difficile academic.oup.com/nar/article/53…

Wiep Klaas Smits (@smitslab) 's Twitter Profile Photo

Discovery of a Widespread Polyamine–Low-Molecular-Weight Thiol Hybrid Pathway in Clostridioides difficile | ACS Infectious Diseases pubs.acs.org/doi/10.1021/ac…

Wiep Klaas Smits (@smitslab) 's Twitter Profile Photo

Comparative genomics of Clostridium butyricum reveals a conserved genome architecture and novel virulence-related gene clusters microbiologyresearch.org/content/journa…