AHHHHH! I CAN'T BELIEVE THIS IS HAPPENING #1MonthTil1989TaylorsVersion

Bad news in #Alzheimer research.. #solanezumab, a drug targeting monomeric amyloid-β species, did not slow cognitive decline in patients with preclinical Alzheimer's in a large cohort of patients. nejm.org/doi/full/10.10…

Rick Riordan on #PercyJackson & The Olympians adaptation: “In terms of the plot, we stuck with it very closely. What I will say though, that I found really fascinating, is that we were able to look at the story, which I wrote back in 2005, and say, “What do I wish I had done at

Now online! The local microenvironment drives activation of neutrophils in human brain tumors dlvr.it/SwhQmL

A Neuroinflammatory battle is happening in this #Alzheimer brain! In the entorhinal cortex, microglia (🟣iba1) and astrocytes (🔵gfap) are gathering forces to fight against neurons accumulating misfolded Tau (🟡AT8). #FluorescenceFriday ZEISS Microscopy

This living human cell 🤩 Inspiring #FluorescenceFriday!

Model showing how bi-directional paracrine signaling between #melanoma cells and keratinocytes potentiates melanoma cell movement. From Hope Burks (Hope Burks) Kathleen Green The Green Lab Northwestern Feinberg School of Medicine and colleagues: bit.ly/3LBdQXd #Cancer #CellSignaling #desmosomes

two neurons having a chat

A new method called PerTurboID identifies proteins that may help to protect the parasite that causes malaria from its host defences. elifesciences.org/digests/86367/….

Principal theories of cancer origins

Scientists can now determine the "molecular age" of your #eyes. Read more in Cell cell.com/cell/fulltext/… Stanford Medicine Vinit Mahajan

Online Now: In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases dlvr.it/SxjlRX

(Likely) Origins of adult cancer

this is so cool!

Isoleucine is an essential amino acid which, in excess, counters the health benefits of the mTOR longevity pathway. The Lamming Lab is reporting that an isoleucine-restricted diet extends the lifespan of mice by 33% 👏 Cell Metabolism

ONLINE NOW: Reprogramming endothelial cells to empower cancer immunotherapy dlvr.it/SzZ0bS

Online Now: Phenotypic signatures of circulating neoantigen-reactive CD8+ T cells in patients with metastatic cancers dlvr.it/SzZvYb

Online Now: Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells dlvr.it/T3Tzrr

You need to be buying *physical* books. Here’s why:

Online Now: CAR T cell combination therapies to treat cancer dlvr.it/TB4Z2q