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"A radically new approach to replacing the haematopoietic [blood cell] system.....the potential to be used for other diseases that benefit from depleting lymphocytes and replacing a diseased immune system, such as severe autoimmune diseases, and maybe even HIV infection. nature

UNIVERSAL DISEASED HEMATOPOIETIC SYSTEM REPLACEMENT: Antibody–drug conjugate targeting CD45 & transplantation of CD45-targeting refractory HSCs enables the selective eradication of leukemic cells with preserved hematopoiesis nature Simon Garaudé Romina Matter Marone nature.com/articles/s4158…

Leukemia Therapy Approach "Deletes" Affected Blood System While Transplanting Healthy Stem Cells Researchers say an approach likened to “mixing console for blood systems" could have broad implications beyond hematological malignancies. Learn more: ow.ly/1N6w50RRCC6

Imagine this: ... in vivo gene edit of hematopoiesis for a genetic disease ... ... combined with a second edit (see below) ... ... and then safely removing the unedited cells to heal hematopoiesis! No need to imagine - it's right here!! 👏Team Cimeio Therapeutics nature.com/articles/s4158…

Nature research paper: Selective haematological cancer eradication with preserved haematopoiesis go.nature.com/4aBDWmC

Like a mixing console blending not songs but blood systems: Researchers demonstrate how to specifically shut down a #leukemia-affected blood system and simultaneously build a new one. Department of Biomedicine UniSpitalBaselCH unibas.ch/en/News-Events…

Paper by the JekerLab.

Thank you Yair for following the project and for always being so enthusiastic about it 👏

JekerLab from Department of Biomedicine has developed a new approach to potentially treat leukemia. Congratulations to all the contributors for their work and publication in the journal nature! 👏 Find out more:  nature.com/articles/s4158…

💡 New approaches to #BloodCancer: Standard practice relied on treating it by using high doses of #chemotherapy. Today, new approaches create renewed hope, potentially offering treatment options with minimal side effects. Learn about Caribou Biosciences & others: forbes.com/sites/juergene…

Genetic cloaking of healthy cells opens door to universal blood cancer therapy arstechnica.com/?p=2032102

🔬 An exciting #hematopoietic cell therapy was developed by University of Basel researchers! They found that a CD45 antibody-drug conjugate eradicated aggressive leukemic cells in vivo by using products such as MethoCult™ and StemSpan™. Cimeio Therapeutics: bit.ly/3S89GJS

« Paris 2024 has begun and the French the people who produce the world’s most delicious cheese, finest haute couture and countless other exquisite creations — have delivered what may be the most unique opening ceremony in the history of the Olympic Games » latimes.com/entertainment-…

Very honored that our work has been awarded this year’s DBM Research Prize! Science is a team sport 💪👩‍🔬👨‍🔬

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

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