Science Signaling
@scisignal
Uncovering mechanisms in biology, gaining insights into physiology and disease.
ID: 137777298
https://www.science.org/journal/signaling 27-04-2010 18:46:45
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How do cancers become resistant to #PROTACS? The Duncan lab finds that #cancer cell lines can resist PROTACs through the efflux pump MDR1, but that the approved drug lapatinib resensitizes tumors to these promising therapies in mice. Fox Chase Cancer Center fcld.ly/ulj4mlb
