Kiara Freitag
@sci_frei
PostDoc @IdoAmitLab @WeizmannScience enthusiastic about #glia in neurodegenerative diseases & science communication
ID: 1190745921245589504
02-11-2019 21:42:11
115 Tweet
289 Followers
391 Following
🚨Paper alert 🚨 Our latest research is out in nature! We reveal a surprising new role for the proteasome in innate immunity: generating antimicrobial peptides that can directly disrupt bacterial membranes. 🦠⚡ Weizmann Institute Systems_Immunology_WIS 🔗 nature.com/articles/s4158… 🧵👇
Excited to share our new study that identified Zeb2 as a master regulator controlling the tumor-associated macrophage (TAM) program using a single-cell CRISPR screen with an amazing team! Fadi Sheban T. San Phan Florian Ingelfinger Yosef Lab IdoAmitLab
Come and dive into our crazy single-cell CRISPR screen journey with Zeb2 emerging as the master regulator of the tumor macrophage program. Thanks to the incredible team effort with Fadi Sheban Ken Xie Florian Ingelfinger IdoAmitLab Yosef Lab 🥳 🚉
Exciting new work identifying Zeb2 as a master regulator controlling TAMs! Congrats to the core team Fadi Sheban T. San Phan Ken Xie Florian Ingelfinger and all other authors!
🚨Registrations now live! Check out this amazing line up of speakers at #RTN #ReThinkNeuroimmunology, organised by Fran Quintana Lab beth stevens Jonathan Kipnis 💔🎗️ IdoAmitLab Rejane Rua Register here: genelayinstitute.org/rtn/
Excited to share our study in Science Immunology dissecting the immune landscape of psoriatic arthritis (PsA)—with a new finding: immunoproteasome overactivity drives treatment resistance🧵 Led by Reut Tzemach,Chamutal Gur,T. San Phan,Eyal David & team. (1/11) science.org/doi/10.1126/sc…
In @NatRevGenet we outline strategies for in vivo pooled (single cell) CRISPR screens for genotype → phenotype mapping in animal models. This contains over a decade of hard earned knowledge by us and the field. Kudos to Antonio Santinha & Alessio Strano. rdcu.be/eykft