Can binding sites on miR200-Zeb axis, which is crucial in regulating EMT - an imp. mechanism for cancer progression and metastasis, be targeted to control phenotypic heterogeneity? Here's our answer. link.springer.com/article/10.100… Thanks to DSTIndia & SERB for the funding.

Happy to share our new preprint. A 2-node +ive feedback loop with an autoloop is the "minimal" network to exhibit tristability (3 attractors). It can explain abrupt as well as smooth-state-swap cell transitions. arxiv.org/abs/2404.05379 NetScience Mohit Kumar Jolly

A heady confluence of physical and life sciences focused on questions in form, development and disease takes place on June 21-22 in IISc. Spread the word! sites.google.com/iisc.ac.in/phy…

Biologists, stop putting UMAP plots in your papers! UMAP is a powerful tool for exploratory data analysis, but without a clear understanding of how it works, it can easily lead to confusion and misinterpretation. Link to Simply Statistics blogpost below.

Registration open for 'Physics of Cells & Tissues 3.0' IISc Bangalore (Feb 21-22, 2025) - an exciting lineup of 22 speakers working on intracellular dynamics, active matter, cellular decision-making & mechanobiology. sites.google.com/iisc.ac.in/phy… BE, IISc Bangalore Developmental Biology Club Physics, IISc

Excellent opportunity for early exposure to Math/Comp Oncology and training with the best mentors at the best place.

A smooth academic career.

Two funded openings in our group (morphogenesisiisc.wixsite.com/home) 1. for a project assistant to study drug resistance and multicellularity in cancer and 2. for a postdoctoral fellow to work on biophysical properties of cancer cells. Interested folks please email me at [email protected]

Hello IRCTC, irctc AIR is down from Friday. Sadly, so far, there is no official update about it. Any idea about if/when it will be restored would be appreciated. RailwaySeva Ministry of Railways

As many know, Professor V. Balakrishnan is a distinguished Indian theoretical physicist and educator whose career spans over five decades. Both his research and teaching are widely recognised. His courses range from introductory mechanics to quantum field theory and chaos, a very