H3K9me3 is not sufficient for silencing endogenous retroviruses if DNA methylation is perturbed. In Dnmt1 ko endoderm cells, IAP elements fully maintain H3K9me3, while trancriptionally active. great collaboration with Heiko Lickert out in Nature Communications rdcu.be/cVRqS

We are recruiting! Come and join our growing team in hematopoiesis and leukemia research in an outstanding environment UAB Heersink School of Medicine UAB O'Neal Comprehensive Cancer Center!

Excited to share our latest work @nature on 3D genome organization alteration in AML. Great collaboration with Hong Zheng, Leonidas Platanias, MD Aaron Viny Ross Levine Yarui Diao and many others. Led by two outstanding students Jie and Fan. nature.com/articles/s4158…

Interesting new paper with an important message - normal clone-to-clone variability is an important confounder in CRISPR experiments. nature.com/articles/s4159…

Our work on ENTER is finally out Cell! Like📱that can 📷📞🎧, ENTER is a modular viral platform that unifies multiple applications: ⭐️Decode Ligand-Receptor interaction ⭐️Receptor-specific cargo delivery ⭐️Link receptor specificity with cell state at single cell

Loss of epigenetic information as a cause of mammalian aging: Cell cell.com/cell/fulltext/…

I would like to share with you our new work on the identification of the first bona fide 'reader' of #histone H3K79 methylation, which has been a mystery since the discovery of this modification in 2002. science.org/doi/10.1126/sc… today online in Science Magazine

Do you (want to) use whole-plasmid sequencing (e.g. plasmidsaurus) but are put off by $15/sample? Use SAVEMONEY—Masaaki Uematsu’s algorithm that lets you mix 6 or more plasmids/sample & computationally de-mixes reads! colab.research.google.com/github/Masaaki… biorxiv.org/content/10.110… How it works: 1/n

Big congrats to my student Sajesan Aryal for being selected by ASH to receive the ASH Graduate Hematology Award (AGHA) [loom.ly/t7i8IC4]! So proud of your work and achievement! UAB Department of Medicine UAB GBS #ASHAwards #proudPI

🤗 On this #FeelGoodFriday we're thrilled to congratulate GBS student Sajesan Aryal for being named a 2023 ASH Graduate Awardee to pursue his research in the lab of Dr. Rui Lu. We're so proud, Sajesan! Keep up the excellent work! UAB O'Neal Comprehensive Cancer Center Rui LU

Breaking news: NIH selects Jeanne Marrazzo as director of the National Institute of Allergy and Infectious Diseases uab.edu/news/people/it…

Outstanding science and collaborators at our The Mark Foundation for Cancer Research retreat! Look for our science coming soon! Ferrell Lab Stanley Lee Rui LU

Way to go! Congratulations, Xinyue!

Demis -- I think AlphaFold3 is really exciting. As Reviewer #3, I got great results from the server. I tried hard to get nature to urge you to release the code but was unsuccessful. I did not get it for re-review so I don't know if you responded. So why no code? Google DeepMind

It is bittersweet to say farewell to Seth Landefeld and wish him well on his next endeavor During his time as chair of UAB Department of Medicine UAB Heersink School of Medicine he has established a path of excellence. His visionary leadership & dedication have left a mark on UAB, inspiring growth & innovation

On April 30, Dr. Barry Sleckman, Director of UAB O'Neal Comprehensive Cancer Center, testified before the U.S. Senate Appropriations Committee during the Biomedical Research: Keeping America’s Edge in Innovation hearing. Watch his powerful testimony: (starting at 52:00) appropriations.senate.gov/hearings/biome…

Online Now: Chromatin-bound U2AF2 splicing factor ensures exon inclusion dlvr.it/TKVRpb