Ruggero La Rosa (@rug_lrs) 's Twitter Profile
Ruggero La Rosa

@rug_lrs

Senior Scientist at @Rigshospitalet and @DTUBiosustain.
Working on #metabolism, #Pseudomonas aeruginosa, #cysticfibrosis, #antibioticresistance, #evolution

ID: 1184863314008039426

calendar_today17-10-2019 16:06:56

115 Tweet

218 Followers

201 Following

Ruggero La Rosa (@rug_lrs) 's Twitter Profile Photo

Are you interested in molecular microbiology and host-pathogen interactions? Then join our team at Rigshospitalet and DTU Biosustain! We are looking for a Post-Doc. Please RT

Ruggero La Rosa (@rug_lrs) 's Twitter Profile Photo

I am very happy to be one of the authors involved in this monumental work to decipher antibiotic resistance to aminoglycosides in #Pseudomonas aeruginosa! A great collaboration between DTU Biosustain CPRatUCPH and Rigshospitalet

Pablo Laborda (@pablolaborda95) 's Twitter Profile Photo

Check out this cool work from my very talented labmates Antonella Colque Ruggero La Rosa @soerenmolin that explores in detail the evolutionary trajectories followed by P. aeruginosa in human airways👇👇

Ruggero La Rosa (@rug_lrs) 's Twitter Profile Photo

Are you interested in host-pathogen interactions and want to become our new cell biologist? Then, join our group of clinicians, cell biologist and microbiologist at Rigshospitalet and DTU Biosustain to tackle the problem of persistent infection! Pls RT tinyurl.com/mxuryme2

NCCR AntiResist (@nccr_antiresist) 's Twitter Profile Photo

Introducing our speakers @nacarb_2024 #nacarb24 Dr. Ruggero La Rosa Ruggero La Rosa researches how bacteria optimise their growth and metabolic activity in response to infection DTU Biosustain Rigshospitalet 👉 Full conference and submission info biozentrum.unibas.ch/events/confere…

Introducing our speakers @nacarb_2024 #nacarb24

Dr. Ruggero La Rosa <a href="/rug_lrs/">Ruggero La Rosa</a> researches how bacteria optimise their growth and metabolic activity in response to infection <a href="/DTUBiosustain/">DTU Biosustain</a> <a href="/Rigshospitalet/">Rigshospitalet</a>

👉 Full conference and submission info biozentrum.unibas.ch/events/confere…
Antonella Colque (@tonecolque) 's Twitter Profile Photo

First project from my PostDoc at Department of Clinical Microbiology Rigshospitalet has been accepted and already published on MBE 🥳 Many thanks to everyone involved in this article DTU Biosustain Check it out!👉🏻academic.oup.com/mbe/article/do…

Ruggero La Rosa (@rug_lrs) 's Twitter Profile Photo

Is historical contingency so important after decades of evolution? Check out our new work on the adaptive evolution of #Pseudomonas aeruginosa in #CF patients! It was a pleasure collaborating on this project!

Ruggero La Rosa (@rug_lrs) 's Twitter Profile Photo

New preprint out! Our latest work challenges the conventional belief that #Pseudomonas aeruginosa is intrinsically resistant to #Macrolides and shows that mutations in uL4 and uL22 ribosomal proteins lead to antibiotic resistance! biorxiv.org/content/10.110…

Ruggero La Rosa (@rug_lrs) 's Twitter Profile Photo

Excited to share our new paper on PLOS Biology: we reveal that secretion of pyruvate by #pseudomonas aeruginosa modifies the #CF host environment and its immune response limiting pathogenicity and favouring persistence DTU Biosustain Rigshospitalet journals.plos.org/plosbiology/ar…

PLOS Biology (@plosbiology) 's Twitter Profile Photo

What's the role of #metabolism in bacterial persistence during infections? Ruggero La Rosa &co show that host-specialized metabolic adaptations in #Pseudomonas aeruginosa reduce virulence & immune responses in #CysticFibrosis patients #CF #PLOSBiology plos.io/4dZFusF

What's the role of #metabolism in bacterial persistence during infections? <a href="/rug_lrs/">Ruggero La Rosa</a> &amp;co show that host-specialized metabolic adaptations in #Pseudomonas aeruginosa reduce virulence &amp; immune responses in #CysticFibrosis patients #CF #PLOSBiology plos.io/4dZFusF
ImmunoSketch (@immunosketch) 's Twitter Profile Photo

Bacteria adapt to survive in harsh conditions, becoming less harmful over time, much like campers learning to live in harmony with nature. Ruggero La Rosa PLOS Biology #Pseudomonas journals.plos.org/plosbiology/ar…

Ruggero La Rosa (@rug_lrs) 's Twitter Profile Photo

An amazing representation of our work by ImmunoSketch. Through metabolic specialisation, #Pseudomonas aeruginosa modifies the host response and attenuates its virulence as a survival strategy. Thanks for the Sketch!

Ruggero La Rosa (@rug_lrs) 's Twitter Profile Photo

New paper out. Despite the wrong assumption of intrinsic resistance, #Pseudomonas aeruginosa is susceptible to macrolides. Ribosomal mutations cause resistance, leading to reduced virulence and increased persistence. Congrats to Lise Goltermann! rdcu.be/dW9uq

New paper out. Despite the wrong assumption of intrinsic resistance, #Pseudomonas aeruginosa is susceptible to macrolides. Ribosomal mutations cause resistance, leading to reduced virulence and increased persistence. Congrats to <a href="/LiseGoltermann/">Lise Goltermann</a>!
rdcu.be/dW9uq
Lise Goltermann (@lisegoltermann) 's Twitter Profile Photo

Very proud of this work! Check out how extended macrolide treatment of #Pseudomonas aeruginosa leads to ribosomal mutations and consequently reduced virulence and possibly increased persistence in #CF and PCD patients! DTU Biosustain Rigshospitalet Ruggero La Rosa Pablo Laborda

Pablo Laborda (@pablolaborda95) 's Twitter Profile Photo

Our new paper is out in Nature Communications! This work led by Lise Goltermann & Ruggero La Rosa questions the prevailing view of intrinsic macrolide resistance in P. aeruginosa-these antibiotics are effective in infection conditions, driving resistance mutations linked to bacterial persistence

ScienceNews (@sciencenewsdk) 's Twitter Profile Photo

People with cystic fibrosis use macrolides to modulate the #immunesystem, but a new study shows that macrolides can make the #bacteria resistant. Researchers say that this is a problem because developing #antimicrobialresistance changes the behaviour of the bacteria, which can

People with cystic fibrosis use macrolides to modulate the #immunesystem, but a new study shows that macrolides can make the #bacteria resistant. Researchers say that this is a problem because developing #antimicrobialresistance changes the behaviour of the bacteria, which can
Ruggero La Rosa (@rug_lrs) 's Twitter Profile Photo

Our group is looking for a PostDoc with a strong background in molecular microbiology, strain design and genetic engineering. Join us at Rigshospitalet and DTU to work on bacterial infections and #AMR. Please RT and apply! tinyurl.com/3kt2yxmj

Ruggero La Rosa (@rug_lrs) 's Twitter Profile Photo

Why are "Pseudomonas aeruginosa infections so difficult to treat—even when #AMR isn’t the main factor? In our latest opinion paper, we explore emerging persistence mechanisms and present the latest concepts in the field. dlvr.it/TL3brB

Ruggero La Rosa (@rug_lrs) 's Twitter Profile Photo

Why are "Pseudomonas aeruginosa infections so difficult to treat—even when #AMR isn’t the main factor? In our latest opinion paper, we explore emerging persistence mechanisms and present the latest concepts in the field. dlvr.it/TL3brB

Sara Hernando-Amado (@besaraornottobe) 's Twitter Profile Photo

I am very happy to share our latest study on ciprofloxacin resistance instability in P. aeruginosa during periods of drug restriction. A fantastic collaboration Pablo Laborda, Ruggero La Rosa, JL Martínez, Søren Molin & Helle Johansen🥳 Centro Nacional de Biotecnología (CSIC) DTU Biosustain nature.com/articles/s4146…