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Faculty position at Karolinska, in the wonderful Solna campus across the street from us at SciLifeLab.

The study "PARKIN is not required to sustain OXPHOS function in adult mammalian tissues" by Roberta Filograna et al now online: biorxiv.org/cgi/content/sh… PARKIN loss does not impair OXPHOS function in different tissues of ageing mice or in skeletal muscle of an adult human patient.

New preprint from us! Paradoxically, daily treatment of obese mice with inhibitors of mitochondrial transcription (IMT) prevents diabetes and hepatosteatosis. The fatty acid oxidation is increased in liver despite a drastic reduction of mtDNA expression: biorxiv.org/content/10.110…

Two neighboring cells can be so different! Releasing scDVP - single-cell #DeepVisualProteomics for combined imaging and mass spectrometry-based proteomics in the intact tissue context. One cell at a time. nature.pulse.ly/13a4oy6x1y Nature Methods Here’s a summary! (1/n)

Please see our latest mitochondrial transcription review, together with Ben Tan Benedict Tan: nature.com/articles/s4158…

Are you interested in understanding the molecular basis of mitochondrial DNA disease? We are looking for enthusiastic PostDocs to join the group of Nils-Göran Larsson (Nils-Göran Larsson) within Division of Molecular Metabolism, KI at Karolinska Institutet, Stockholm. ki.varbi.com/en/what:job/jo…

PostDoc opportunity! We are looking for an enthusiastic #PostDoc to study how mitochondrial dysfunction contributes to the pathogenesis of neurodegenerative disease. Join my research group within Division of Molecular Metabolism, KI Karolinska Institutet ki.varbi.com/en/what:job/jo…

Just a few days left to apply for a #Postdoc position! Join us in the vibrant work environment at Division of Molecular Metabolism, KI in Stockholm!

I have the honor and pleasure of co-organizing the EMBO workshop on Molecular Biology of Mitochondrial Gene Maintenance & Expression, with an amazing lineup of speakers! Join us in Poland from May 19-23! Early-carreer researchers especially encouraged! meetings.embo.org/event/24-mitoc…

Our study is finally out! nature.com/articles/s4153… We here show that PARKIN is dispensable for OXPHOS function in adult mouse tissues and in skeletal muscle from a PD-patient. Thanks to Nils-Göran Larsson , Motori Lab, Thomas Perlmann and Per Svenningsson for the great collaboration!

New paper from us on the in vivo role of the LRPPRC/SLIRP protein complex and its crucial role in mammalian mtDNA gene expression: academic.oup.com/nar/advance-ar… Congratulations Diana Rubalcava for great work! Thank you to all coauthors for a very nice collaboration.

We are excited to share our lab's first preprint, highlighting the role of the CHCHD2-CHCHD10 complex in preserving tissue homeostasis. A huge thank you to all our collaborators! biorxiv.org/content/10.110…

Happy to share our latest manuscript on using quantitative proteomics to diagnose patients with mitochondrial disease. Great collaboration with Taylor Lab and Lukas Käll insight.jci.org/articles/view/…

🚨Mitochondrial research out🚨 Our latest work on the synergy between LRPPRC and SLIRP for maintaining mtDNA gene expression in vivo is now published! 🧬 Free-access link to the article: academic.oup.com/nar/article/52…

🚨Save the date!🚨 Co-organized by our CRC1218 PI, Elisa Motori EMBO Workshop “Mitochondria in the Nervous System” 🧠⚡ in beautiful Engelberg, Switzerland 🗓 Sept 29 - Oct 2, 2025 Spaces are limited, keep an eye out for registration! #Mitochondria #BrainScience #EMBOWorkshop

New study from us: science.org/doi/10.1126/sc… High mtDNA copy number promotes lung cancer growth in the mouse, whereas mtDNA depletion in tumor cells reduces tumor growth. This tumor-intrinsic role for mtDNA can be exploited for development of future lung cancer therapies.

We are excited to share our latest work on mechanisms that protect from mitochondrial dysfunction. Thank you to all collaborators and the 4th anonymous reviewer for supporting us. Matthias Mann Lab Nature Communications Florian Rosenberger nature.com/articles/s4146…

🚨PostDoc Alert! We are looking for an enthusiastic and driven #PostDoc to study the role of mitochondrial dysfunction in neurodegenerative diseases. Join my research group Division of Molecular Metabolism, KI within Karolinska Institutet! #Mitochondria #Neurodegeneration #MitoJobs ki.varbi.com/se/what:job/jo…

Interested in mitochondrial biology? We are looking for an enthusiastic PostDoctoral fellow and PhD student to join our group in Stockholm. mitojobs Division of Molecular Metabolism, KI For the PhD position: kidoktorand.varbi.com/what:job/jobID… For the PostDoc position: ki.varbi.com/what:job/jobID…

Exciting news from Pretzel Therapeutics! We’ve launched a Phase 1 trial for our POLG activator—PX578—targeting rare mito. syndromes with potential for Parkinson’s & Alzheimer’s diseases Congratulations to the entire team—proud to be part of this journey! pretzeltx.com/pretzel-therap…