Our pre-print is out!! Proud to share our work as part of the world’s first human #COVID-19 challenge study, in which we looked to temporally resolve the epithelial and immune response in SARS-CoV-2 infections at the single-cell level. 🧬🦠🔬 Key highlights summarised👇🧵(1/6)

Excited to share STAPLER, a language model to predict TCR – pMHC reactivity that outperforms prior models. And for ML aficionados: Description of a new data leakage problem inherent to a common negative data generation strategy. biorxiv.org/content/10.110… 🧵👇

Do different host transcriptional biomarkers of acute viral infection offer different clinical and research applications? Insights from SARS-CoV-2 human challenge in our new PREPRINT: medrxiv.org/content/10.110…

The NKI opened an exciting new call and PhD program for students interested in Chromosome Biology and Gene Regulation!

Congratulations to Piet Borst, 2023 #LaskerAward winner! – “for an exceptional 50-year career of scientific discovery, mentorship, and leadership”. ow.ly/cuFl50PNTMJ #Lasker2023 #LaskerLaureate #mtDNA #mitochondria #trypanosomes

Thrilled to share my journey as a new junior PI at The Netherlands Cancer Institute, featured in Nature Cancer. From overcoming the challenges of setting up a lab to building a team and plotting a scientific course.

Stoked to see this tour-the-force from the Bartke team out in Nature! We've decoded how DNA & histone modifications regulate protein binding to the genome using quantitative interaction proteomics. A leap forward in understanding chromatin dynamics! Congrats to everyone involved!

Nature research paper: Decoding chromatin states by proteomic profiling of nucleosome readers go.nature.com/3P7kNRC

Honored to be among the recipients of the NWO Open Competition M1 grant! We will develop tools to improve our understanding of TCR-antigen interactions, using high-throughput screening & AI. Stay tuned for a postdoc vacancy to join this exciting project! nwo.nl/en/news/ninete…

I'm #hiring a #postdoc to join my research group at the NKI in Amsterdam. Are you interested in developing state-of-the-art genomics and proteomics technologies to study TCR : antigen interactions in cancer? Apply before the 8th of May: nki.nl/careers-study/… #AcademicTwitter

I'm #hiring a PhD student! Join the Lindeboom Lab at the The Netherlands Cancer Institute on an exciting project to explore oncogenic transcription factor binding kinetics and biophysics using state-of-the-art technologies! Apply now or share this exciting opportunity! nki.nl/careers-study/…

Excited to share that we received the Technology Impact Award from Cancer Research Institute to develop methods to study immune - cancer cell interactions for identifying proteins and antigens that modulate cancer cell killing, and targets for immunotherapy! cancerresearch.org/cri-funded-sci…

Happy and proud to receive the ERC Starting grant! We will investigate how genome-wide binding kinetics and energy landscapes of oncogenic transcription factors are regulated! Interested in joining our team? Apply before the 22th of Sept. #ERCStG nki.nl/news-events/ne…

Passionate about doing innovative, curiosity-driven research and looking to start your own lab? The NKI has an opening for a Junior Group Leader position! Join us in our collaborative environment in Amsterdam, to use our state-of-the-art infrastructure to make a real impact.

Exciting news for aspiring PhD students: the NKI PhD Program 2025 will open soon for applications! We participate with multiple top labs in this prestigious program, which offers a unique opportunity for PhD candidates to engage in cutting-edge genome biology and cancer research.