🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Super grateful and happy to be part of MATCHMAKERS and CGC!

Thank you Cancer Grand Challenges team for disseminating our study on osteosarcoma cell.com/cell/fulltext/… Incredibly excited to present this and other stories from the lab on complex cancer genomes at such an unparalleled venue The Royal Society! Thanks Team #eDyNAmiC for the invite! 🙏🙌

Our focus issue features reviews and research articles that explore emerging ideas about patterns in molecular biology, highlighting connections across key molecular mechanisms and their collective contribution to the function of the cell. cell.com/molecular-cell….

Join us The Royal Society in June for the first conference focused on all things extrachromosomal DNA! In addition to this incredible line-up we have plenty of spots for selected talks too, submit your abstract now!

Today in nature we share our back-to-back stories with Ning Zheng revealing chemical-genetic convergence between a molecular glue & E3 ligase cancer mutations. 1/6

The first paper from the #Cancer_Neuroscience Lab The Francis Crick Institute just got published in nature ! Checkout how lung cancer cells form their own electrical network and use that to promote malignancy, and how #intratumoural_heterogeneity and #lactate_shuttle play a role in that👉

🚨2 weeks left to submit your abstract on ecDNAs for the first ever ecDNA-focussed conference! Don't miss out on this historical moment!

Read more about the 7 new #CancerGrandChallenges in this commentary published today: aacrjournals.org/cancerdiscover…

Exciting news for the cancer research community! Read more about the new challenges now in Cancer Discovery: doi.org/10.1158/2159-8…

New Challenges just announced!! £20m per international team! -The dark proteome -Mechanisms driving mutational signatures -AI-human collaborations in cancer -Cancer avoidance -The nervous system and cancer -Rewiring cancer cells -TME dynamics More info: cancergrandchallenges.org/new-challenges…

Join our very own Rita Cha at the Cancer Grand Challenges Challenges Conference on extrachromosomal DNA (ecDNA) this June in London. For more details about the conference and registration, check out: dlvr.it/TJVmQV

We are finalizing the programme of our Cancer Grand Challenges Challenges Conference on #ecDNAs (June, London🇬🇧), and I couldn't be more proud and excited! Watch this space for updates! Also, register soon as we're nearly sold out! 👇 cancergrandchallenges.org/ecDNA-2025

In Focus: Tackling Cancer through Global Team Science brnw.ch/21wS5fm By Rebecca Eccles, Gabriela Carreno, Lorenzo de la Rica (he/him), Gemma Balmer-Kemp, and David Scott Cancer Grand Challenges Cancer Research UK National Cancer Institute #CancerGrandChallenges

🚨New in nature Mutographs identified mutational signatures caused by the bacterial genotoxin colibactin are enriched in early onset colorectal cancer cases Read more about the findings, the open questions and the curiosities of colibactin 👇 features.cancerresearchuk.org/cancergrandcha…

🧠 How do tumours and the nervous system talk—and to what end? This question drives one of 7 open #CancerGrandChallenges. Our team explores it in a new Neuron perspective. 📖 Read the full article:bit.ly/42MpdVh 📅 EOIs open until 18 June

Exceptional work from Rushika M. Perera identifies differential utilization of PCSK9 / cholesterol synthesis pathways and regulation of #ferroptosis as key determinants of pancreatic cancer metastasis. 🔥🤩 nature.com/articles/s4158…

Excited to unveil Boltz-2, our new model capable not only of predicting structures but also binding affinities! Boltz-2 is the first AI model to approach the performance of FEP simulations while being more than 1000x faster! All open-sourced under MIT license! A thread… 🤗🚀

Move over AlphaFold3. Boltz-2 has arrived, bringing affinity prediction for protein-small molecule interactions! Can’t wait to see what this group does next. It was a pleasure writing this piece. Thanks to Regina Barzilay & Jeremy Wohlwend, and congratulations to all involved!

A massive thank you to everyone at #CGCecDNA, especially our co-organisers Mischel Lab, Mariam Jamal-Hanjani and Howard Chang, and all of our fantastic speakers! Together we’ll tackle the challenge of extrachromosomal DNA.